| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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Italian pool of asbestos workers cohorts
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Country
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Name
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Daniela Ferrante
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Institution
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Università del Piemonte Orientale, Italy
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Email
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daniela.ferrante@med.uniupo.it
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Phone
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+393332053889
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Do you want to add another Principal Investigator of the Cohort
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- Add another Principal Investigator of the cohort
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Name
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Corrado Magnani
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Email
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corrado.magnani@med.uniupo.it
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Name of committee
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University of Eastern Piedmont Ethical Review Board (Authorisation CE 112/13, 12 July 2013)
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Upload files
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Contact Principal Investigator (name)
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Daniela Ferrante
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Participation in pooled analyses
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- The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
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Main aim of cohort, please briefly describe the main objectives of the cohort
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We aimed at including as many as possible Italian cohorts already investigated in the past with mortality follow-up and providing, once updated, an observation period >40 years
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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- Industry / occupation-based
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Comparators (please select as many as appropriate)
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- Internal study population
- External study population (includes SMR/SIR studies)
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Inclusion criteria
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After a literature search including also unpublished reports, eligible cohorts were identified, principal investigators invited, data updated and pooled.
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Enrollment
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Completed
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Age range at entry (main cohort)
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| Minimum |
Maximum |
Mean |
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67 |
28 |
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Men at enrollment
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46060
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Women at enrollment
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5741
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Children (<18 years) at enrollment
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4574
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Men at last follow-up
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44411
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Women at last follow-up
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5529
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Children (<18 years) at last follow-up
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4417
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| 2. OUTCOME FOLLOW-UP |
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Type of data for outcome follow-up (please select as many as appropriate)
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Death certificate (specify)
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- The Registrar’s Offices of the town of residence were accessed to obtain the information on vital status.The causes of death were provided by the Local Health Authority Registries of Causes of Death for decedents after 1985 and by the Registrar Office of the municipality where death occurred for earlier years
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First follow-up period (provide year)
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1950
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Last follow-up period (provide year)
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2014
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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Occupational history/time frame
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Follow-up period
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Occupational coding performed
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No
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Types of exposure measurements
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Specify: Other
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Two expert industrial hygienists collected and evaluated the information regarding the use of asbestos, the work process, the plant layout and the measurements of airborne asbestos fibres, for each plant and year of activity. Considered data sources included both published and unpublished reports, in particular company reports, surveys of exposure, judicial examinations, and reports collected from workers
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Methods for exposure assessment (please select as many as appropriate)
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Main categories
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Dusts and fibres | Fibres
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- Asbestos (any form of asbestos chrysotile, crocidolite, tremolite, anthophyllite, etc. or asbestos-containing material)
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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Outcome type (please select as many as appropriate)
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Diagnostic groups based on ICD10
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- C + D Neoplasms
- J Respiratory disease
- K Diseases of oesophagus, stomach, duodenum and appendix
- K Diseases of peritoneum, liver
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C + D Neoplasms
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- Malignant neoplasms gastro intes. system including liver, gall bladder, pancreas
- Malignant neoplasm lung
- Mesothelioma
- Other malignant neoplasm of respiratory and intrathoracic organs, heart, pleura
- Malignant neoplasms, females gynecological
- Malignant neoplasms of male genital organs
- Malignant neoplasm of urinary tract and kidney
- Malignant neoplasms of ill-defined, secondary and unspecified sites
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J Respiratory disease
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| 6. Other Information |
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Possibility for linkage to data registries/data enrichment via data linkage
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- Cancer incidence
- Mortality register
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Please describe plans that are funded or most likely to be funded
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The planning is to update the follow up and include other cohorts
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