| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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Longitudinal Aging Study Amsterdam
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Country
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Please provide any other information on the cohort location/s if needed
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Three regions in the Netherlands together representing the socio-geographic variation
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Name
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Martijn Huisman
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Institution
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Amsterdam University Medical Centers, location VU medical center, dept of Epidemiology & Biostatistics
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Email
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ma.huisman@amsterdamumc.nl
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Name
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Dorly Deeg
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Institution
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Amsterdam University Medical Centers, location VU medical center, dept of Epidemiology & Biostatistics
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Email
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djh.deeg@amsterdamumc.nl
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Website
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Name of committee
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VU University Medical Center - Medical Ethics Testing Committee
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Upload files
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Or provide website
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Data access policy (briefly describe)
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https://lasa-vu.nl/data/availability_data/availability_data.htm
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Participation in pooled analyses
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- The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
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Main aim of cohort, please briefly describe the main objectives of the cohort
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To determine predictors and consequences of changes in functioning with aging, including physical, emotional, cognitive and social functioning of older persons (55+) in the Netherlands.
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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- General population: National
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Comparators (please select as many as appropriate)
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- Internal study population
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Inclusion criteria
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None: random sample from population registries
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Exclusion criteria
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None
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Enrollment
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Completed
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Age range at entry (main cohort)
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| Minimum |
Maximum |
Mean |
| 55 |
85 |
70 |
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Men at enrollment
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2477
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Women at enrollment
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2655
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Children (<18 years) at enrollment
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-
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Men at last follow-up
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661
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Women at last follow-up
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732
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Children (<18 years) at last follow-up
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-
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Participation rate at enrollment (if known)
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60
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| 2. OUTCOME FOLLOW-UP |
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Type of data for outcome follow-up (please select as many as appropriate)
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- Active (contact with participants)
- Death certificate
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Active (contact with participants) (specify)
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- 3-yearly main measurement cycles and in-between side studies
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Death certificate (specify)
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- Vital status or respondent and spouse from municipal basic administrations
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First follow-up period (provide year)
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1995
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Last follow-up period (provide year)
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2019
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Number of follow-ups after baseline (provide number)
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3 (most recent cohort) - 9 (earliest cohort)
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Participation at last follow-up (if known)
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92
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Comments
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participation rate excluding deaths from denominator
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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- Questionnaire, Personal (Self-reporting or interview)
- Questionnaire, Personal (Occupational/industry modules)
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Occupational history/time frame
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Current, at enrollment
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Occupational coding performed
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Yes
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Occupation (specify coding system used)
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- Netherlands Standard Classification of Occupations 1992 and 2010
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Industry (specify coding system used)
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- Netherlands Standard Classification of Occupations 1992 and 2010
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Types of exposure measurements
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Specify: Other
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work demands and resources
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Methods for exposure assessment (please select as many as appropriate)
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- Job Exposure Matrix
- Self-report
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Specify: Job Exposure Matrix / Other
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General Population JEM for older workers
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Website
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https://lasa-vu.nl/themes/work/GPJEM.htm
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Main categories
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- Ergonomics, physical workload, and injury related
- Psychosocial domains
- Organisation of work including working time
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Ergonomics, physical workload, and injury related
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- Awkward work postures (e.g. kneeling/squatting, elevated arms, neck flection, back bent forward without support)
- Physical work load (e.g. heavy lifting of people or objects, pushing/pulling)
- Repetitive work movements
- Sedentary work
- Standing work
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Psychosocial domains | Job task characteristics/organization of work
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- Effort-reward imbalance (ERI)
- Job control, autonomy
- Psychological job demands
- Social support at work from supervisors
- Skill use opportunities
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Organisation of work including working time | Employment conditions
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- Work contract type (i.e. permanent, term-contract, subcontract, temporary)
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Organisation of work including working time | Shift work
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- Night (permanent or rotating)
- Rotating (not night)
- Regular/variable
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Organisation of work including working time | Working hours
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- Duration
- Regular/variable
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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- Death certificates
- Medical records
- Questionnaire, individual (self-recording or interview)
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Follow-up - type of outcome data collected (select more than one if applicable)
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- Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
- Death certificates
- Medical records
- Questionnaire, individual (self-recording or interview)
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Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
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physical performance tests, grip strength, peak expiratory flow, blood pressure, heart rae, cognitive tests
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Outcome type (please select as many as appropriate)
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- Mortality
- Morbidity
- Disability
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Other health related outcomes
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- Biomarkers
- Lifestyle change
- Quality of life/wellbeing
- Sleep
- Work participation
- Other (specify)
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Specify: Other
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cognitive functioning, social engagement
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| 5. BIOLOGICAL SAMPLES & ANALYSIS |
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Biological samples collected
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Biological processing
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Genetic and other lab analyses
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- Biomarkers (specify)
- Genomics / GWAS
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Specify: Biomarkers
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https://lasa-vu.nl/themes/biomaterial/biomaterial_submenu.html
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| 6. Other Information |
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- Alcohol
- Anthropometry
- Demographics
- Diet
- Education
- Environmental, air pollution
- Environmental other (specify)
- Medical history
- Personality
- Physical exercise
- Residential history
- Socioeconomic status
- Smoking
- Other (specify)
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Specify: Environmental other
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area-code based, see https://bmjopen.bmj.com/content/8/6/e021597
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Specify: Other
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See masterlist at the bottom of this page: https://lasa-vu.nl/index.htm
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Possibility for linkage to data registries/data enrichment via data linkage
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- Birth register
- Cancer incidence
- Hospital discharge
- Mortality register
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Please describe plans that are funded or most likely to be funded
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Most recently funded:
- "Healthy on the way to retirement (f/m)? Changes in the health of older female and male workers depending on their gender identity and work demands" (Netherlands Organisation for Health Rersearch and Development)
- “Secular trends in employment of older workers in the Netherlands and Norway: how influential are policy regulations?" (Network for Studies on Pensions, Aging and Retirement)
Most recently submitted:
- "Vulnerability and vitality of older persons during the corona crisis" (including changes in work participation)
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