Date of filling in this questionnaire or last update: 22/05/2020
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  Healthy Hands Project
Country
 

  • Netherlands

Please provide any other information on the cohort location/s if needed
  Amsterdam
Name
  Sanja Kezic
Institution
  Amsterdam UMC
Email
  s.kezic@amc.uva.nl
Phone
  +31205665321
Personal website
  https://www.amc.nl/web/research-75/person-1/phd-s.-kezic.htm
Name of committee
  METC AMC
Upload files
 

Contact Principal Investigator (name)
  Sanja Kezic
Data access policy (briefly describe)
  Data are available on request
Is this cohort part of a consortium? (name consortium)
  no
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).

Main aim of cohort, please briefly describe the main objectives of the cohort
  Study on the effect of wet work activities on development of contact dermatitis
Study design (please select as many as appropriate)
 

  • Prospective cohort

Source population (please select as many as appropriate)
 

  • Hospital / patient-based

Comparators (please select as many as appropriate)
 

  • Internal study population

Inclusion criteria
  Enrollement on traineeship for at leat 10 weeks
Exclusion criteria
  Presence of a chronic inflammatory disease
Enrollment
  Completed
Age range at entry (main cohort)
 

Minimum Maximum Mean
18.3 20.9 19.5

Men at enrollment
  71
Women at enrollment
  649
Men at last follow-up
  60
Women at last follow-up
  506
Participation rate at enrollment (if known)
  95
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Disease incidence records

Disease incidence records (specify)
 

  • Use of questionnaires, diagnosis based on self reported symptoms of hand dermatitis

First follow-up period (provide year)
  2008
Last follow-up period (provide year)
  2011
Number of follow-ups after baseline (provide number)
  3
Participation at last follow-up (if known)
  74
Comments
  Not all participatnts had 3 follow-ups, this was dependent on the time within the cohort period when they were enrolled
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Questionnaire, Personal (Self-reporting or interview)

Occupational history/time frame
  Follow-up period
Occupational coding performed
  No
Methods for exposure assessment (please select as many as appropriate)
 

  • Self-report

Main categories
 

  • Solvents
  • Other chemicals

Solvents | Organic solvents, other than aliphatic, aromatic and chlorinated
 

  • Alcohols

Other chemicals | Detergents and cleaning products
 

  • Detergents

Comments
  the main risk factor in health care workers is so called wet work which includes water, detergents and alcohol disenfectants
4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Questionnaire, individual (self-recording or interview)

Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Questionnaire, individual (self-recording or interview)

Diagnostic groups based on ICD10
 

  • L Skin, nail and hair disorders

L Skin, nail and hair disorders
 

  • Atopic dermatitis
  • Allergic contact dermatitis
  • Irritant contact dermatitis

5. BIOLOGICAL SAMPLES & ANALYSIS
Biological samples collected
 

  • Other

Specify: Other
  buccal swab
Biological processing
 

  • DNA

Genetic and other lab analyses
 

  • Genomics / Other genetics (specify)

Specify: Other genetics
  Filaggrin loss-of-function mutations
6. Other Information
 

  • Demographics
  • Education
  • Medical history