| 1. IDENTIFICATION & BASIC DESCRIPTION |
|
Cohort name
|
| |
Generation XXI
|
|
Country
|
| |
|
|
Please provide any other information on the cohort location/s if needed
|
| |
Porto
|
|
Name
|
| |
Henrique Barros
|
|
Email
|
| |
henrique.barros@ispup.up.pt
|
|
Website
|
| |
- http://www.geracao21.com/en/
|
|
Name of committee
|
| |
Ethics Committee of São João Hospital/University of Porto Medical School
|
|
Contact Principal Investigator (name)
|
| |
Henrique Barros and Ana Cristina Santos
|
|
Participation in pooled analyses
|
| |
- The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
|
|
Main aim of cohort, please briefly describe the main objectives of the cohort
|
| |
To understand the influence of prenatal and early life years in the development and health during adolescence and adulthood.
|
|
Source population (please select as many as appropriate)
|
| |
- General population: Regional
- Mother-child cohort
|
|
Comparators (please select as many as appropriate)
|
| |
- Internal study population
|
|
Inclusion criteria
|
| |
All women resident in Porto metropolitan area who delivered a live-born child with more than 23 weeks of gestation in a public maternity unit, between April 2005 and August 2006.
|
|
Enrollment
|
| |
Completed
|
|
Men at enrollment
|
| |
4435
|
|
Women at enrollment
|
| |
8495
|
|
Children (<18 years) at enrollment
|
| |
8647
|
|
Participation rate at enrollment (if known)
|
| |
91.4
|
| 2. OUTCOME FOLLOW-UP |
|
Type of data for outcome follow-up (please select as many as appropriate)
|
| |
- Active (contact with participants)
- Death certificate
|
|
First follow-up period (provide year)
|
| |
2009-2011
|
|
Number of follow-ups after baseline (provide number)
|
| |
4
|
|
Participation at last follow-up (if known)
|
| |
70
|
| 3. OCCUPATIONAL EXPOSURES |
|
Source of exposure data collected (please select as many as appropriate)
|
| |
- Questionnaire, Personal (Self-reporting or interview)
|
|
Occupational history/time frame
|
| |
Follow-up period
|
|
Occupational coding performed
|
| |
Yes
|
|
Occupation (specify coding system used)
|
| |
- Portuguese Classification of Occupations 2010, based on ISCO-08
|
|
Methods for exposure assessment (please select as many as appropriate)
|
| |
|
|
Main categories
|
| |
- Physical agents
- Ergonomics, physical workload, and injury related
- Psychosocial domains
- Organisation of work including working time
|
|
Physical agents
|
| |
- Hand-arm vibration
- Whole body vibration
|
|
Ergonomics, physical workload, and injury related
|
| |
- Awkward work postures (e.g. kneeling/squatting, elevated arms, neck flection, back bent forward without support)
- Physical work load (e.g. heavy lifting of people or objects, pushing/pulling)
- Repetitive work movements
- Sedentary work
- Work with video display units (VDU)
|
|
Psychosocial domains | Job task characteristics/organization of work
|
| |
- Career advancement opportunities
- Job control, autonomy
- Social support at work from supervisors
- Skill use opportunities
|
|
Physical agents | Work/non-work interface
|
| |
- Work-family (work-home) interface/conflict/balance
|
|
Organisation of work including working time | Employment conditions
|
| |
|
| 4. OUTCOMES EVALUATED |
|
Baseline - type of outcome data collected (select more than one if applicable)
|
| |
- Biomarker (specify)
- Medical records
- Questionnaire, individual (self-recording or interview)
|
|
Follow-up - type of outcome data collected (select more than one if applicable)
|
| |
- Biomarker (specify)
- Questionnaire, individual (self-recording or interview)
|
|
Outcome type (please select as many as appropriate)
|
| |
- Mortality
- Morbidity
- Disability
|
|
Diagnostic groups based on ICD10
|
| |
- C + D Neoplasms
- E Endocrinological disease
- E Malnutrition and obesity
- F Mental disorders
- I Heart disease
- I Cerebrovascular diseases
- J Respiratory disease
- M Arthritis, arthrosis, systemic connective disorders, spine disorders
- M Disorders of muscles, bones, synovialis, bursa, cartilage
- N Kidney, renal pelvis disease
- O+P Pregnancy and labour
- Q After birth – child disorders
- S Injuries
|
|
E Endocrinological disease
|
| |
- Thyroidea
- Diabetes mellitus
|
|
I Heart disease
|
| |
- Hypertensive diseases
- Angina pectoris
- Acute myocardial infarction
- Heart failure
|
|
I Cerebrovascular diseases
|
| |
- Stroke, not specified as haemorrhage or infarction
|
|
O+P Pregnancy and labour
|
| |
- Eclampsia in pregnancy, labour or puerperium
- Diabetes mellitus in pregnancy
- Preterm delivery
- Other low birth weight
|
|
Other health related outcomes
|
| |
- Biomarkers
- Lifestyle change
- Sleep
- Work participation
|
| 5. BIOLOGICAL SAMPLES & ANALYSIS |
|
Biological samples collected
|
| |
|
|
Specify: Other
|
| |
teeth
|
|
Genetic and other lab analyses
|
| |
|
| 6. Other Information |
|
|
| |
- Alcohol
- Anthropometry
- Demographics
- Diet
- Education
- Medical history
- Physical exercise
- Residential history
- Socioeconomic status
- Smoking
|
|
Possibility for linkage to data registries/data enrichment via data linkage
|
| |
- Hospital discharge
- Mortality register
|
