| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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FAIR
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Country
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Please provide any other information on the cohort location/s if needed
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National cohort
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Name
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Jenny Selander
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Institution
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Karolinska Institutet
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Email
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jenny.selander@ki.se
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Phone
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+46852480029
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Personal website
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https://ki.se/en/imm/research/units-at-imm/unit-of-occupational-medicine-0
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Website
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- https://ki.se/en/imm/research/units-at-imm/unit-of-occupational-medicine-0
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Contact Principal Investigator (name)
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Jenny Selander
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Data access policy (briefly describe)
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Data is locked on secure servers, can be accessed by collaboration and/or research affiliation to KI
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Is this cohort part of a consortium? (name consortium)
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No
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Main aim of cohort, please briefly describe the main objectives of the cohort
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Birth cohort on the national population in Sweden
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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- General population: National
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Inclusion criteria
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All births between 1994 and 2014, (is being updated to 2024)
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Exclusion criteria
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None for full cohort, but occupational analyses will usually only include the working population
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Enrollment
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Ongoing
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Age range at entry (main cohort)
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| Minimum |
Maximum |
Mean |
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30 |
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Age range at entry (subcohort)
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| Minimum |
Maximum |
Mean |
Please describe |
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0 |
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Men at enrollment
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50% (1 million)
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Women at enrollment
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50% (1 million)
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Children (<18 years) at enrollment
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all (2 million)
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Men at last follow-up
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1 million
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Women at last follow-up
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1 million
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Children (<18 years) at last follow-up
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1,1 million
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Participation rate at enrollment (if known)
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100
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Comments
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Registry based cohort, where all births in Sweden are included, for now born between 1994 and 2014, addition up to 2024 will be added.
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| 2. OUTCOME FOLLOW-UP |
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Type of data for outcome follow-up (please select as many as appropriate)
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- Hospital / physician diagnoses
- Use of registers (specify)
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Hospital / Physician diagnoses (specify)
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- Patient registry, medical birth registry, cause of death registry
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Specify: Use of registers
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First follow-up period (provide year)
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Followed up continously, every year from 1995
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Last follow-up period (provide year)
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to 2024
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Number of follow-ups after baseline (provide number)
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Every year 30 years in total
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Participation at last follow-up (if known)
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98
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Comments
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Complete follow up, but a few die or emigrate.
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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- Registry-based
- Other (specify)
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Specify: Other
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Occupational hygenist have manually coded free text into occupational codes
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Occupational history/time frame
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Current, at enrollment
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Occupational coding performed
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Yes
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Occupation (specify coding system used)
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- AMSYK a 6-digit version of SSYK-96 (based on ISCO-88-COM)
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Methods for exposure assessment (please select as many as appropriate)
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- Data modelling
- GIS (other spatial methods)
- Expert assessment
- Job Exposure Matrix
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Specify: Job Exposure Matrix / Other
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SweJEM
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Website
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https://ki.se/en/imm/swejem
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Main categories
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- Dusts and fibres
- Solvents
- Pesticides
- Metals and metal oxides
- Other chemicals
- Physical agents
- Ergonomics, physical workload, and injury related
- Psychosocial domains
- Organisation of work including working time
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Dusts and fibres | Fibres
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- Asbestos (any form of asbestos chrysotile, crocidolite, tremolite, anthophyllite, etc. or asbestos-containing material)
- Fibres (not specified)
- Glass wool
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Dusts and fibres | Inorganic dusts
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- Carbon black
- Inorganic dusts, not specified
- Quartz (quartz or crystalline silica containing dusts)
- Stone (Natural or Artificial)
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Dusts and fibres | Organic dusts
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- Animal dust (from living animals or hairs of animals, e.g. raw wool, furs of minks, etc.)
- Flour dust
- Leather dust
- Organic dusts (not specified)
- Plant dust (includes plants, fruits, vegetables, plant-borne materials such as natural rubber)
- Pulp or paper dust
- Textile dust
- Wood dust (hardwood)
- Wood dust (softwood)
- Wood dust (not specified)
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Solvents | Aliphatic and alicyclic hydrocarbon solvents
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Solvents | Aromatic hydrocarbon solvents
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- Benzene
- Styrene and styrene oxide
- Toluene
- Xylene
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Solvents | Chlorinated hydrocarbon solvents
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Solvents | Organic solvents, other than aliphatic, aromatic and chlorinated
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Metals and metal oxides
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- Arsenic all types
- Chromium (metallic chromium, Cr(iii), Cr(vi) and all compounds)
- Iron (metallic iron and all compounds)
- Lead and all compounds
- Mercury, organic, inorganic
- Nickel and all compounds
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Other chemicals | Carbon monoxide
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Other chemicals | Engine exhaust
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- Diesel engine exhaust
- Gasoline engine exhaust
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Other chemicals | Polycyclic aromatic hydrocarbons (PAHs)
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- Asphalt/Bitumen fumes
- Benzo(a)pyrene
- Bitumen fumes
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Other chemicals | Welding fumes
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- Welding fumes, not specified
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Physical agents
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- Cold
- Hand-arm vibration
- Heat
- Noise
- Whole body vibration
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Ergonomics, physical workload, and injury related
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- Awkward work postures (e.g. kneeling/squatting, elevated arms, neck flection, back bent forward without support)
- Physical work load (e.g. heavy lifting of people or objects, pushing/pulling)
- Repetitive work movements
- Standing work
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Psychosocial domains | Job task characteristics/organization of work
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- Job control, autonomy
- Psychological job demands
- Social support at work from supervisors
- Other (specify)
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Psychosocial domains | Job task characteristics/organization of work | Specify: Other
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Emotional demands
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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Registry-based
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- Birth register
- Cancer incidence
- Disease specific clinical database
- Employment status
- Hospital discharge
- Medication usage
- Mortality register
- Migration
- Other
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Specify: Other
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Insurence etc.
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Follow-up - type of outcome data collected (select more than one if applicable)
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Registry-based
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- Cancer incidence
- Disease specific clinical database
- Employment status
- Hospital discharge
- Medication usage
- Mortality register
- Migration
- Other
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Outcome type (please select as many as appropriate)
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- Mortality
- Morbidity
- Disability
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Diagnostic groups based on ICD10
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- C + D Neoplasms
- E Endocrinological disease
- E Metabolism disease
- F Mental disorders
- H Disorders of the ear
- I Heart disease
- J Respiratory disease
- O+P Pregnancy and labour
- Q After birth – child disorders
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C + D Neoplasms
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- Benign neoplasm
- Carcinoma in situ
- Leukemia
- Malignant neoplasms gastro intes. system including liver, gall bladder, pancreas
- Malignant neoplasm lung
- Mesothelioma
- Other malignant neoplasm of respiratory and intrathoracic organs, heart, pleura
- Malignant neoplasm of bone and articular cartilage
- Melanoma and other malignant neoplasms of skin
- Neoplasms connective and soft tissue including nerves
- Malignant neoplasm of breast
- Malignant neoplasms, females gynecological
- Malignant neoplasms of male genital organs
- Malignant neoplasm of urinary tract and kidney
- Malignant neoplasms of eye, brain and other parts of central nervous system
- Malignant neoplasms of thyroid and other endocrine glands
- Malignant neoplasms of ill-defined, secondary and unspecified sites
- Malignant neoplasm without specification of site including excl. leukemia
- Other, please state
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E Endocrinological disease
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F Mental disorders
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- Mood [affective] disorders
- Depression
- Disorders of psychological development including autism and Aspergers syndrome
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H Disorders of the ear
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- Diseases of middle ear and mastoid
- Diseases of inner ear
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O+P Pregnancy and labour
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- Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
- Eclampsia in pregnancy, labour or puerperium
- Diabetes mellitus in pregnancy
- Complications of labour and delivery
- Preterm delivery
- Extremely low birth weight
- Other low birth weight
- Exceptionally large baby
- Birth trauma
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| 6. Other Information |
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- Anthropometry
- Demographics
- Education
- Environmental, air pollution
- Environmental other (specify)
- Medical history
- Residential history
- Socioeconomic status
- Smoking
- Other (specify)
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Specify: Environmental other
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many variables
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Specify: Other
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many varibles
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Possibility for linkage to data registries/data enrichment via data linkage
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- Birth register
- Cancer incidence
- Disease specific clinical database
- Employment status
- Hospital discharge
- Medication usage
- Migration
- Mortality register
- Other (specify)
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Specify: Other
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all Swedish
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Please describe plans that are funded or most likely to be funded
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Have current funded project that uses this cohort, have active staff that can run analyses.
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