| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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Workers biologically monitored (solvents)
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Country
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Name
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Sanni Uuksulainen
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Institution
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Finnish Institute of Occupational Health
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Email
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Sanni.Uuksulainen@ttl.fi
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Contact Principal Investigator (name)
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Sanni Uuksulainen
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Main aim of cohort, please briefly describe the main objectives of the cohort
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To provide monitoring data on six solvents: styrene, toluene, xylene, tetrachloroethylene, trichlorethylene and 1,1,1-trichloroethane among exposed Finnish workers during 1965-83
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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- Industry / occupation-based
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Inclusion criteria
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Individuals were identified based on availability of biological measurement of six organic solvents analyzed at FIOH during 1965-1983.
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Exclusion criteria
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Unknown personal identity code
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Enrollment
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Completed
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Men at enrollment
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5931
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Women at enrollment
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3194
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| 2. OUTCOME FOLLOW-UP |
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Type of data for outcome follow-up (please select as many as appropriate)
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- Death certificate
- Use of registers (specify)
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Specify: Use of registers
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- sickness absence, pensions
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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Occupational history/time frame
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Current, at enrollment
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Occupational coding performed
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Yes
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Occupation (specify coding system used)
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Types of exposure measurements
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- Biomarkers (see also section 5)
- Workplace sampling
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Methods for exposure assessment (please select as many as appropriate)
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- Job Exposure Matrix
- Measurements (external sampling, biomarkers)
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Main categories
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Solvents | Aromatic hydrocarbon solvents
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- Styrene and styrene oxide
- Toluene
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Solvents | Chlorinated hydrocarbon solvents
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- Trichloroethanes
- Trichloroethylene
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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Follow-up - type of outcome data collected (select more than one if applicable)
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- Death certificates
- Registry-based
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Registry-based
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- Cancer incidence
- Employment status
- Mortality register
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Outcome type (please select as many as appropriate)
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- Mortality
- Morbidity
- Disability
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Diagnostic groups based on ICD10
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- C + D Neoplasms
- E Metabolism disease
- F Mental disorders
- G Disease in the nervous system
- I Heart disease
- I Cerebrovascular diseases
- J Respiratory disease
- M Arthritis, arthrosis, systemic connective disorders, spine disorders
- M Disorders of muscles, bones, synovialis, bursa, cartilage
- O+P Pregnancy and labour
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C + D Neoplasms
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- Benign neoplasm
- Carcinoma in situ
- Leukemia
- Malignant neoplasms gastro intes. system including liver, gall bladder, pancreas
- Malignant neoplasm lung
- Mesothelioma
- Other malignant neoplasm of respiratory and intrathoracic organs, heart, pleura
- Malignant neoplasm of bone and articular cartilage
- Melanoma and other malignant neoplasms of skin
- Neoplasms connective and soft tissue including nerves
- Malignant neoplasm of breast
- Malignant neoplasms, females gynecological
- Malignant neoplasms of male genital organs
- Malignant neoplasm of urinary tract and kidney
- Malignant neoplasms of eye, brain and other parts of central nervous system
- Malignant neoplasms of thyroid and other endocrine glands
- Malignant neoplasms of ill-defined, secondary and unspecified sites
- Malignant neoplasm without specification of site including excl. leukemia
- Other, please state
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| 5. BIOLOGICAL SAMPLES & ANALYSIS |
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Biological samples collected
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| 6. Other Information |
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Possibility for linkage to data registries/data enrichment via data linkage
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- Cancer incidence
- Employment status
- Mortality register
- Other (specify)
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Specify: Other
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sickness absence, pensions
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