| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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BAMSE
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Country
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Please provide any other information on the cohort location/s if needed
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Stockholm
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Name
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Erik Melén
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Institution
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Karolinska Institutet
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Email
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erik.melen@ki.se
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Phone
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+46-(0)8-524 875 08
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Personal website
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https://staff.ki.se/people/erimel
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Name
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Antonios Georgelis
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Institution
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Center for Occupational and Environmental medicine, Region Stockholm, Sweden
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Email
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antonios.georgelis@sll.se
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Website
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Name of committee
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Swedish Ethical Review Authority
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Upload files
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Contact Principal Investigator (name)
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Erik Melén
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Is this cohort part of a consortium? (name consortium)
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MeDALL
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Participation in pooled analyses
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- The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
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Main aim of cohort, please briefly describe the main objectives of the cohort
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BAMSE stands for children, allergy, environment, Stockholm and epidemiology (the Swedish words barn, allergi, miljö, Stockholm and epidemiologi) and is a collaborative project between Karolinska Institutet and Region Stockholm. The original aim of the project was to study the impact of environmental factors for the development of allergic diseases.
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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- General population: Regional
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Comparators (please select as many as appropriate)
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- Internal study population
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Inclusion criteria
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All children born in certain areas of northern and central Stockholm between Feb 1994 and Nov 1996
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Exclusion criteria
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the family planned to move within 1 year of the study start; insufficient knowledge of the Swedish language; the family had a seriously ill child; or an older sister or brother was already included in the study.
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Enrollment
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Completed
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Age range at entry (main cohort)
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| Minimum |
Maximum |
Mean |
| 2-3 months |
2-3 months |
2-3 months |
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Men at enrollment
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0
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Women at enrollment
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0
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Children (<18 years) at enrollment
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4089
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Men at last follow-up
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1445
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Women at last follow-up
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1619
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Children (<18 years) at last follow-up
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0
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Participation rate at enrollment (if known)
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75
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| 2. OUTCOME FOLLOW-UP |
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Type of data for outcome follow-up (please select as many as appropriate)
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- Active (contact with participants)
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Active (contact with participants) (specify)
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First follow-up period (provide year)
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1
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Last follow-up period (provide year)
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24
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Number of follow-ups after baseline (provide number)
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7
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Participation at last follow-up (if known)
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75
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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- Questionnaire, Personal (Self-reporting or interview)
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Occupational history/time frame
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Current, at enrollment
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Occupational coding performed
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Yes
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Occupation (specify coding system used)
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Methods for exposure assessment (please select as many as appropriate)
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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- Questionnaire, individual (self-recording or interview)
- Registry-based
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Registry-based
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Follow-up - type of outcome data collected (select more than one if applicable)
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- Biomarker (specify)
- Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
- Questionnaire, individual (self-recording or interview)
- Registry-based
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Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
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Spirometry, blood samples etc in the offspring
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Specify: Biomarker
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Urinary metabolites
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Registry-based
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Outcome type (please select as many as appropriate)
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Diagnostic groups based on ICD10
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J Respiratory disease
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| 5. BIOLOGICAL SAMPLES & ANALYSIS |
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Biological samples collected
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Biological processing
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Genetic and other lab analyses
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- Biomarkers (specify)
- Epigenomics
- Genomics / GWAS
- Metabolomics
- Proteomics
- Transcriptomics
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Specify: Biomarkers
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urinary environmental pollutants, OLINK inflammation panel, plasma fatty acids
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| 6. Other Information |
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- Alcohol
- Anthropometry
- Demographics
- Diet
- Education
- Environmental, air pollution
- Environmental other (specify)
- Medical history
- Physical exercise
- Residential history
- Socioeconomic status
- Smoking
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Specify: Environmental other
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Noise
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Possibility for linkage to data registries/data enrichment via data linkage
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- Birth register
- Medication usage
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