Date of filling in this questionnaire or last update: 17/01/2026
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  ECRHS - European Community Respiratory Health Survey
Country
 

  • Algeria
  • Australia
  • Austria
  • Denmark
  • Estonia
  • France
  • Germany
  • Greece
  • Iceland
  • India
  • Ireland
  • Italy
  • Netherlands
  • New Zealand
  • Norway
  • Portugal
  • Spain
  • Sweden
  • Switzerland
  • United Kingdom
  • United States

Name
  Debbie Jarvis
Institution
  Imperial College, London, UK
Email
  d.jarvis@imperial.ac.uk
Personal website
  http://www.imperial.ac.uk/people/d.jarvis
Website
 

  • https://www.ecrhs.org/

Name of committee
  Due to the muticentre structure of ECRHS multiple ethical committees involved
Or provide website
 

  • https://www.ecrhs.org/

Contact Principal Investigator (name)
  Debbie Jarvis
Is this cohort part of a consortium? (name consortium)
  The European Occupational Exposome and Health Cohort Consortium
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).

Main aim of cohort, please briefly describe the main objectives of the cohort
  To provide information about (change in) prevalence and incidence of respiratory disease and allergy, and to identify risk factors and beneficial factors for both development and prognosis of respiratory disease and allergy
Study design (please select as many as appropriate)
 

  • Prospective cohort

Source population (please select as many as appropriate)
 

  • General population: International

Comparators (please select as many as appropriate)
 

  • Internal study population

Enrollment
  Ongoing
Age range at entry (main cohort)
 

Minimum Maximum Mean
20 44

Men at enrollment
  5,000
Women at enrollment
  5,000
Children (<18 years) at enrollment
  0
Men at last follow-up
  3,400
Women at last follow-up
  3,600
Children (<18 years) at last follow-up
  0
Participation rate at enrollment (if known)
  78
Comments
  Overall 78%. Range 54–100, 48 centres.
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Active (contact with participants)

Active (contact with participants) (specify)
 

  • For a subgroup of the population clinical investigations with a focus on lung disease and allergy were performed at baseline and subsequently at two follow-ups

First follow-up period (provide year)
  2026
Participation at last follow-up (if known)
  60
Comments
  Please see flow chart in: Jarvis D. et al Prevalence of asthma-like symptoms with ageing. Thorax. 2018 Jan;73(1):37-48.
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Questionnaire, Personal (Self-reporting or interview)
  • Questionnaire, Personal (Occupational/industry modules)
  • Environmental samples

Occupational history/time frame
  Lifetime
Occupational coding performed
  Yes
Occupation (specify coding system used)
 

  • ISCO88

Types of exposure measurements
 

  • Biomarkers (see also section 5)
  • Personal external sampling

Methods for exposure assessment (please select as many as appropriate)
 

  • Expert assessment
  • Job Exposure Matrix
  • Measurements (external sampling, biomarkers)
  • Self-report

 

  • ALOHA+ JEM

Please insert reference/further information
  Lytras T, et al . Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey. Thorax. 2018 Nov;73(11):1008-1015.
 

  • Asthma JEM

Please insert reference/further information
  Pape et al. Parental occupational exposure pre- and post-conception and development of asthma in offspring. Int J Epidemiol. 2020 Jul 14:dyaa085. doi: 10.1093/ije/dyaa085. Epub ahead of print.
 

  • DOM-JEM

 

  • FIN-JEM

Main categories
 

  • Dusts and fibres
  • Pesticides
  • Other chemicals
  • Ergonomics, physical workload, and injury related
  • Psychosocial domains

Dusts and fibres | Fibres
 

  • Other (specify)

Dusts and fibres | Fibres | Specify: Other
  Fulll job history - JEMs can be applied
Dusts and fibres | Inorganic dusts
 

  • Other (specify)

Dusts and fibres | Inorganic dusts | Specify: Other
  Fulll job history - JEMs can be applied
Dusts and fibres | Organic dusts
 

  • Organic dusts (not specified)

Dusts and fibres | Other
 

  • Other

Dusts and fibres | Other | Specify: Other
  Fulll job history - JEMs can be applied
Pesticides | Fungicides
 

  • Other (specify)

Pesticides | Fungicides | Specify: Other
  Fulll job history - JEMs can be applied
Other chemicals | Detergents and cleaning products
 

  • Cleaning products
  • Detergents

Ergonomics, physical workload, and injury related
 

  • Other (specify)

Ergonomics, physical workload, and injury related | Specify: Other
  Fulll job history - JEMs can be applied
Psychosocial domains | Job task characteristics/organization of work
 

  • Other (specify)

Psychosocial domains | Job task characteristics/organization of work | Specify: Other
  Fulll job history - JEMs can be applied
Comments
  Due to the full job history exposures can be applied where JEMs are available
4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Biomarker (specify)
  • Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
  • Questionnaire, individual (self-recording or interview)

Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
  Lung function, Skin prick test, broncial hyper reactivity
Specify: Biomarker
  IgE
Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Biomarker (specify)
  • Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
  • Questionnaire, individual (self-recording or interview)

Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
  Lung function, Skin prick test, broncial hyper reactivity
Specify: Biomarker
  IgE, for some DNA and GWAS
Outcome type (please select as many as appropriate)
 

  • Morbidity
  • Disability

Diagnostic groups based on ICD10
 

  • E Malnutrition and obesity
  • J Respiratory disease

E Malnutrition and obesity
 

  • Obesity

J Respiratory disease
 

  • Acute bronchitis
  • Vasomotor and allergic rhinitis
  • Chronic rhinitis, nasopharyngitis and pharyngitis
  • Chronic sinusitis
  • Chronic Bronchitis
  • Emphysema
  • Chronic obstructive pulmonary disease (COPD)
  • Asthma

Other health related outcomes
 

  • Biomarkers
  • Lifestyle change
  • Sickness absence
  • Sleep
  • Work participation

5. BIOLOGICAL SAMPLES & ANALYSIS
Biological samples collected
 

  • Blood
  • Sputum
  • Urine
  • Other

Specify: Other
  feces, skin
Biological processing
 

  • DNA

Genetic and other lab analyses
 

  • Biomarkers (specify)
  • Epigenomics
  • Genomics / GWAS
  • Metabolomics

Specify: Biomarkers
  IgE
Comments
  Only genetiic and other lab analysis for sub samples
6. Other Information
 

  • Anthropometry
  • Demographics
  • Diet
  • Education
  • Environmental other (specify)
  • Physical exercise
  • Socioeconomic status
  • Smoking

Specify: Environmental other
  Dust samples from indoor environments, information about cleaning products
Possibility for linkage to data registries/data enrichment via data linkage
 

  • Other (specify)

Specify: Other
  Possible to link to several registers for some centres