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Date of filling in this questionnaire or last update: 07/10/2020
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  AMIGO
Country
 

  • Netherlands
Name
  Roel Vermeulen
Institution
  UU/IRAS
Email
  R.C.H.Vermeulen@uu.nl
Website
 

  • http://www.amigoproject.nl/
  • http://www.lifeworkstudy.nl/
  • http://www.thecosmosproject.org/
Name of committee
  METC UMCU
Or provide website
 

  • See websites mentioned above
Contact Principal Investigator (name)
  Prof. Dr. R. Vermeulen
Data access policy (briefly describe)
  Data is available upon request and a DTA will be created
Is this cohort part of a consortium? (name consortium)
  Lifework and COSMOS
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
Main aim of cohort, please briefly describe the main objectives of the cohort
  We set up the population-based Occupational and Environmental Health Cohort Study (AMIGO) to longitudinally study occupational and environmental determinants of diseases and wellbeing from a multidisciplinary and lifetime point of view. Determinants include chemical, biological, physical (e.g. electromagnetic fields), and psychosocial factors. Priority health outcomes include cancer, neurological, cardiovascular and respiratory diseases and non-specific symptoms. Owing to the recruitment strategy via general practitioners of an established network, we also collect longitudinal data on health outcomes registered in their electronic medical records including symptoms, diagnosis, and treatments. This created the unique opportunity to assess potential health-related participation bias by comparing general practitioner-registered prevalence rates in the cohort and the source population.
Study design (please select as many as appropriate)
 

  • Prospective cohort
Source population (please select as many as appropriate)
 

  • General population: National
Comparators (please select as many as appropriate)
 

  • Internal study population
Inclusion criteria
  We aimed to sample the general adult population of the Netherlands and decided to select 31-65 years olds for various reasons, e.g. working age as occupational exposure is a main determinant, and the age of onset of our main health outpoints. Our recruitment strategy was to invite subjects through 99 general practices that are part of a nation-wide information and surveillance network for primary health care established at NIVEL, i.e. the NIVEL Primary Care Database
Enrollment
  Completed
Age range at entry (main cohort)
 

Minimum Maximum Mean
31 65 50.7

Men at enrollment
  6561
Women at enrollment
  8268
Men at last follow-up
  3726
Women at last follow-up
  4179
Participation rate at enrollment (if known)
  16
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Active (contact with participants)
  • Death certificate
  • Disease incidence records
  • Hospital / physician diagnoses
  • Use of registers (specify)
Active (contact with participants) (specify)
 

  • By sending out questionnaires
Death certificate (specify)
 

  • Mortality outcome (CBS)
Disease incidence records (specify)
 

  • GP registries, questionnaires, Cancer registry
Hospital / Physician diagnoses (specify)
 

  • GP registries
Specify: Use of registers
 

  • CBS, Cancer registry, BRP, GP registry
First follow-up period (provide year)
  2013
Last follow-up period (provide year)
  2015
Number of follow-ups after baseline (provide number)
  3 (2014 in subcohort)
Participation at last follow-up (if known)
  53
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Questionnaire, Personal (Self-reporting or interview)
  • Questionnaire, Personal (Occupational/industry modules)
Occupational history/time frame
  Lifetime
Occupational coding performed
  No
Methods for exposure assessment (please select as many as appropriate)
 

  • Data modelling
  • GIS (other spatial methods)
  • Self-report
4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Death certificates
  • Medical records
  • Questionnaire, individual (self-recording or interview)
  • Registry-based
Registry-based
 

  • Cancer incidence
  • Mortality register
Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Death certificates
  • Medical records
  • Questionnaire, individual (self-recording or interview)
  • Registry-based
Registry-based
 

  • Cancer incidence
  • Mortality register
Outcome type (please select as many as appropriate)
 

  • Mortality
  • Morbidity
Other health related outcomes
 

  • Sleep
6. Other Information
 

  • Alcohol
  • Demographics
  • Diet
  • Education
  • Environmental, air pollution
  • Environmental other (specify)
  • Medical history
  • Physical exercise
  • Residential history
  • Socioeconomic status
  • Smoking
Specify: Environmental other
  several exposures, such as EMF, noise
Possibility for linkage to data registries/data enrichment via data linkage
 

  • Cancer incidence
  • Mortality register