| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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Born in Bradford
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Country
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Please provide any other information on the cohort location/s if needed
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Bradford, UK
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Name
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John Wright
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Institution
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Bradford Teaching Hospitals NHS Foundation Trust
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Email
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john.wright@bthft.nhs.uk
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Phone
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01274 36 4279
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Personal website
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Website
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- https://borninbradford.nhs.uk/
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Name of committee
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Bradford Research Ethics Committee
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Upload files
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Or provide website
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- https://borninbradford.nhs.uk/research/
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Data access policy (briefly describe)
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Requests for existing data and biological samples will be reviewed, prioritised and authorised by the BiB Executive Group. The Investigator should complete an outline proforma available on the Born in Bradford website (borninbradford.nhs.uk) and submit to: borninbradford@bthft.nhs.uk
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Main aim of cohort, please briefly describe the main objectives of the cohort
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The cohort was established in 2007 with the broad aims to: describe health and ill health within a multi-ethnic (largely bi-ethnic) economically deprived population; identify modifiable causal pathways that promote well-being or contribute to ill health; develop, design and evaluate interventions to promote health; provide a model for integrating operational, epidemiological and evaluative research into practice within the National Health Service and other health-related systems; and build and strengthen local research capacity in Bradford.
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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Inclusion criteria
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All women planning to give birth at the BRI will be eligible for recruitment, regardless of parity.
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Exclusion criteria
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The only exclusion criterion for recruitment of a woman will be if she plans to move away from Bradford before the birth.
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Enrollment
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Completed
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Age range at entry (subcohort)
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| Minimum |
Maximum |
Mean |
Please describe |
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49 |
27 |
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Men at enrollment
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3448
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Women at enrollment
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12453
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Children (<18 years) at enrollment
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13858
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Men at last follow-up
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On-going
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Women at last follow-up
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On-going
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Children (<18 years) at last follow-up
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On-going
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| 2. OUTCOME FOLLOW-UP |
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Type of data for outcome follow-up (please select as many as appropriate)
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- Active (contact with participants)
- Disease incidence records
- Hospital / physician diagnoses
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Comments
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Please refer to our study documents on the Born in Bradford webpage (https://borninbradford.nhs.uk/research/study-documents/) for information on data collected and all follow-ups.
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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- Questionnaire, Personal (Self-reporting or interview)
- Breath samples
- Environmental samples
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Occupational history/time frame
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Current, at enrollment
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Occupational coding performed
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Yes
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Occupation (specify coding system used)
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Types of exposure measurements
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- Biomarkers (see also section 5)
- Personal external sampling
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Methods for exposure assessment (please select as many as appropriate)
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- Data modelling
- GIS (other spatial methods)
- Measurements (external sampling, biomarkers)
- Self-report
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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- Biomarker (specify)
- Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
- Medical records
- Questionnaire, individual (self-recording or interview)
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Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
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Please refer to the Born in Bradford data dictionary: https://borninbradford.github.io/datadict/
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Specify: Biomarker
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Please refer to the Born in Bradford data dictionary: https://borninbradford.github.io/datadict/
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Follow-up - type of outcome data collected (select more than one if applicable)
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- Biomarker (specify)
- Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
- Medical records
- Questionnaire, individual (self-recording or interview)
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Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
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Please refer to the Born in Bradford data dictionary: https://borninbradford.github.io/datadict/
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Specify: Biomarker
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Please refer to the Born in Bradford data dictionary: https://borninbradford.github.io/datadict/
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Outcome type (please select as many as appropriate)
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- Mortality
- Morbidity
- Disability
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Comments
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Born in Bradford collects and has data linkage to a wide range of data, including hospital and GP records. Please refer to the Born in Bradford data dictionary for detailed information: https://borninbradford.github.io/datadict/
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| 5. BIOLOGICAL SAMPLES & ANALYSIS |
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Biological samples collected
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Biological processing
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Genetic and other lab analyses
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- Biomarkers (specify)
- Epigenomics
- Genomics / GWAS
- Genomics / Other genetics (specify)
- Metabolomics
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Specify: Biomarkers
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Please refer to the Born in Bradford data dictionary: https://borninbradford.github.io/datadict/
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Specify: Other genetics
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Exome sequencing
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Comments
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Please refer to the Born in Bradford data dictionary: https://borninbradford.github.io/datadict/
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| 6. Other Information |
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- Alcohol
- Anthropometry
- Demographics
- Diet
- Education
- Environmental, air pollution
- Medical history
- Physical exercise
- Residential history
- Socioeconomic status
- Smoking
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Possibility for linkage to data registries/data enrichment via data linkage
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- Birth register
- Hospital discharge
- Medication usage
- Mortality register
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