| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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ALSPAC (Avon Longitudinal Study of Parents and Children)
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Country
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Please provide any other information on the cohort location/s if needed
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Bristol, South West England
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Name
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Ni Timpson
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Institution
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University of Bristol
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Email
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n.j.timpson@bristol.ac.uk
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Website
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- http://www.bristol.ac.uk/alspac/researchers/
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Name of committee
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Multiple
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Or provide website
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- http://www.bristol.ac.uk/alspac/researchers/
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Contact Principal Investigator (name)
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alspac-exec@bristol.ac.uk
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Data access policy (briefly describe)
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Available on website
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Participation in pooled analyses
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- The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
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Main aim of cohort, please briefly describe the main objectives of the cohort
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Birth cohort study (multi-generational)
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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- General population: Regional
- Mother-child cohort
- Generation (parents-children) study
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Inclusion criteria
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pregnant women, date of 199delivery between April 91 and October 92, resident in Bristol health authorities
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Enrollment
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Completed
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Age range at entry (main cohort)
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| Minimum |
Maximum |
Mean |
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39.7 years |
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Men at enrollment
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6000
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Women at enrollment
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14000
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Participation rate at enrollment (if known)
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85
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| 2. OUTCOME FOLLOW-UP |
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First follow-up period (provide year)
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1991
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Last follow-up period (provide year)
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2020
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Number of follow-ups after baseline (provide number)
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many
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Participation at last follow-up (if known)
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40
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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- Questionnaire, Personal (Self-reporting or interview)
- Environmental samples
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Occupational history/time frame
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Follow-up period
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Occupational coding performed
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Yes
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Occupation (specify coding system used)
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Types of exposure measurements
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- Biomarkers (see also section 5)
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Methods for exposure assessment (please select as many as appropriate)
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- Data modelling
- GIS (other spatial methods)
- Self-report
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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- Biomarker (specify)
- Death certificates
- Medical records
- Questionnaire, individual (self-recording or interview)
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Follow-up - type of outcome data collected (select more than one if applicable)
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- Biomarker (specify)
- Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
- Death certificates
- Medical records
- Questionnaire, individual (self-recording or interview)
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Outcome type (please select as many as appropriate)
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Other health related outcomes
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- Biomarkers
- Lifestyle change
- Quality of life/wellbeing
- Sleep
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| 5. BIOLOGICAL SAMPLES & ANALYSIS |
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Biological samples collected
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Biological processing
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Genetic and other lab analyses
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- Biomarkers (specify)
- Epigenomics
- Genomics / GWAS
- Metabolomics
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| 6. Other Information |
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- Alcohol
- Anthropometry
- Demographics
- Diet
- Education
- Environmental, air pollution
- Environmental other (specify)
- Medical history
- Personality
- Physical exercise
- Residential history
- Socioeconomic status
- Smoking
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Possibility for linkage to data registries/data enrichment via data linkage
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- Cancer incidence
- Hospital discharge
- Medication usage
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