EPHOR participating cohorts

The Trøndelag Health Study (HUNT)

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Date of filling in this questionnaire or last update: 21/12/2025

1. IDENTIFICATION & BASIC DESCRIPTION Cohort name   The Trøndelag Health Study (HUNT) Country   Norway Name   Steinar Krokstad Institution   Norwegian University of Science and Technology Email   steinak@ntnu.no Phone   +4795219227 Personal website   https://www.ntnu.no/ansatte/steinar.krokstad Website   https://www.ntnu.no/hunt Name of committee   Central Regional Committee for Medical and Health Research, Norway Upload files   HUNT-Cohort-Profile-2012-IJE-Krokstad-et-al.pdf Data access policy (briefly describe)   Data are available for research projects upon application and after REC approval. https://www.ntnu.no/hunt/forskning Is this cohort part of a consortium? (name consortium)   The European Occupational Exposome and Health Cohort Consortium Participation in pooled analyses   The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses). Source population (please select as many as appropriate)   General population: Regional Comparators (please select as many as appropriate)   Internal study population External comparison of workers with other exposure Inclusion criteria   The total adult population in the Trøndelag County Norway Enrollment   Ongoing Age range at entry (main cohort)   Minimum Maximum Mean 13 (20 adult) 101 51 Men at enrollment   66.000 with occupational information Women at enrollment   56.000 with occupational information Children (<18 years) at enrollment   8,000 Men at last follow-up   25,468 with occupational information Women at last follow-up   30,574 with occupational information Children (<18 years) at last follow-up   8,066 Participation rate at enrollment (if known)   89 2. OUTCOME FOLLOW-UP Type of data for outcome follow-up (please select as many as appropriate)   Active (contact with participants) Death certificate Disease incidence records Active (contact with participants) (specify)   New surveys every decade Death certificate (specify)   National Causes of Death Register Disease incidence records (specify)   Several national disease specific registers First follow-up period (provide year)   1984 Last follow-up period (provide year)   2019 Number of follow-ups after baseline (provide number)   4 Participation at last follow-up (if known)   54 3. OCCUPATIONAL EXPOSURES Source of exposure data collected (please select as many as appropriate)   Questionnaire, Personal (Self-reporting or interview) Questionnaire, Personal (Occupational/industry modules) Breath samples Occupational history/time frame   Follow-up period Occupational coding performed   Yes Occupation (specify coding system used)   Norwegian Occupational Classification Industry (specify coding system used)   Industry branches Types of exposure measurements   Biomarkers (see also section 5) Methods for exposure assessment (please select as many as appropriate)   Measurements (external sampling, biomarkers) Self-report Main categories   Solvents Pesticides Dusts and fibres | Organic dusts | Specify: Other   Dust in general Solvents | Other   Other Solvents | Other | Specify: Other   Solvents in general Pesticides | Fungicides   Mancozeb 4. OUTCOMES EVALUATED Baseline - type of outcome data collected (select more than one if applicable)   Biomarker (specify) Death certificates Medical records Questionnaire, individual (self-recording or interview) Registry-based Specify: Biomarker   Blood samples Registry-based   Birth register Cancer incidence Disease specific clinical database Employment status Hospital discharge Medication usage Mortality register Migration Follow-up - type of outcome data collected (select more than one if applicable)   Biomarker (specify) Questionnaire, individual (self-recording or interview) Registry-based Specify: Biomarker   Blood samples Registry-based   Birth register Cancer incidence Employment status Hospital discharge Medication usage Mortality register Migration Outcome type (please select as many as appropriate)   Mortality Morbidity Disability Diagnostic groups based on ICD10   A Bacterial infectious disease, type of microorganisms* B Viral infections, type of microorganisms* B99 Other and unspecified infectious diseases, type of microorganisms* C + D Neoplasms D Diseases of blood and blood-forming organs excl. leukemia E Endocrinological disease E Malnutrition and obesity E Metabolism disease F Mental disorders G Disease in the nervous system H Disorders of the eye H Disorders of the ear I Heart disease I Cerebrovascular diseases J Respiratory disease K Diseases of oral cavity, salivary glands and jaws K Diseases of oesophagus, stomach, duodenum and appendix K Hernia, colon and intestine disease K Diseases of peritoneum, liver L Skin, nail and hair disorders M Arthritis, arthrosis, systemic connective disorders, spine disorders M Disorders of muscles, bones, synovialis, bursa, cartilage N Kidney, renal pelvis disease N Male and female related disorders O+P Pregnancy and labour Q After birth – child disorders S Injuries Other health related outcomes   Biomarkers Lifestyle change Sickness absence Sleep Work participation 5. BIOLOGICAL SAMPLES & ANALYSIS Biological samples collected   Blood Urine Biological processing   DNA RNA Genetic and other lab analyses   Biomarkers (specify) Epigenomics Genomics / GWAS Specify: Biomarkers   Blood available 6. Other Information   Alcohol Anthropometry Demographics Diet Education Physical exercise Socioeconomic status Smoking Possibility for linkage to data registries/data enrichment via data linkage   Birth register Cancer incidence Employment status Hospital discharge Medication usage Migration Mortality register

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