| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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DOC*X
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Country
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Name
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Esben Meulengracht Flachs
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Institution
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Bispebjerg and Frederiksberg Hospital, University of Copenhagen
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Email
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esben.meulengracht.flachs@regionh.dk
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Phone
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+045 35313531
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Website
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Name of committee
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Danish National Committee on Health Research Ethics
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Or provide website
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Contact Principal Investigator (name)
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Esben Meulengracht Flachs
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Participation in pooled analyses
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- The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
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Main aim of cohort, please briefly describe the main objectives of the cohort
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To build a large nationwide database that can integrates prospective data on occupational exposures with data on health, work participation and labour market exits
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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- General population: National
- Industry / occupation-based
- Hospital / patient-based
- Mother-child cohort
- Generation (parents-children) study
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Comparators (please select as many as appropriate)
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- Internal study population
- External comparison of workers with other exposure
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Inclusion criteria
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Persons aged at least 16 years who were gainfully employed and living in Denmark in 1970 and from 1976 to 2018
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Enrollment
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Ongoing
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Age range at entry (main cohort)
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| Minimum |
Maximum |
Mean |
| 16 |
105 |
35 |
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Age range at entry (subcohort)
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| Minimum |
Maximum |
Mean |
Please describe |
| 0 |
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Children of parents in the main cohort |
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Men at last follow-up
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2984000
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Women at last follow-up
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2414000
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Comments
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In 2015 the cohort included 6,399,000 individuals - 2,984,000 men and 2,414,000 women.
JEM based exposures in the database:
- Psychosocial exposures (permission needed from JEM owners)
- Shoulder exposures (upper arm elevation, repetitive shoulder movements, forceful shoulder exertions)
- Lower body exposures (total load lifted, standing/walking, sitting, kneeling/squatting)
- Physical exertion and body position (score based on sitting, standing/walking, kneeling, repetition, twisted back, lifted arms, lifting/carrying, pushing/pulling)
- Noise
- Vibration
- Particulate airborne exposures (mineral dust, organic dust, fumes and vapour) (permission needed from JEM owners)
- Wood and endotoxin
- Chemical agents (permission needed from JEM owners)
- Lifestyle (tobacco smoking, body mass index, alcohol consumption, leisure-time physical activity, fruit/vegetables consumption)
- Wet hands and gloves
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| 2. OUTCOME FOLLOW-UP |
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Type of data for outcome follow-up (please select as many as appropriate)
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- Death certificate
- Disease incidence records
- Hospital / physician diagnoses
- Use of registers (specify)
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Death certificate (specify)
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- Access to Cause of Death register
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Disease incidence records (specify)
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- Access to the Danish Patient Registry
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Hospital / Physician diagnoses (specify)
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First follow-up period (provide year)
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1976
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Last follow-up period (provide year)
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1918
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Number of follow-ups after baseline (provide number)
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Once per year
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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Occupational history/time frame
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Follow-up period
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Occupational coding performed
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Yes
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Occupation (specify coding system used)
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- DISCO-88 (Danish version of ISCO-88)
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Industry (specify coding system used)
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Methods for exposure assessment (please select as many as appropriate)
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Please insert reference/further information
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Permission needed from owners
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Main categories
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- Dusts and fibres
- Solvents
- Pesticides
- Metals and metal oxides
- Other chemicals
- Biological factors
- Ergonomics, physical workload, and injury related
- Psychosocial domains
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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- Death certificates
- Medical records
- Registry-based
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Registry-based
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- Birth register
- Disease specific clinical database
- Hospital discharge
- Mortality register
- Migration
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Follow-up - type of outcome data collected (select more than one if applicable)
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- Death certificates
- Medical records
- Registry-based
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Registry-based
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- Birth register
- Employment status
- Hospital discharge
- Mortality register
- Migration
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Outcome type (please select as many as appropriate)
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- Mortality
- Morbidity
- Disability
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| 6. Other Information |
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- Alcohol
- Demographics
- Diet
- Education
- Medical history
- Physical exercise
- Residential history
- Socioeconomic status
- Smoking
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Possibility for linkage to data registries/data enrichment via data linkage
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- Birth register
- Employment status
- Hospital discharge
- Migration
- Mortality register
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Please describe plans that are funded or most likely to be funded
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Exposure to air pollution
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