Date of filling in this questionnaire or last update: 17/04/2021
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  Norwegian Working Age Cohort (born 1930-92)
Country
 

  • Norway

Please provide any other information on the cohort location/s if needed
  Total population born 1930-1992, residing in Norway 2000-2010, registry-based (N = 3 898 165)
Name
  Ingrid Sivesind Mehlum
Institution
  STAMI (National Institute of Occupational Health), Oslo, Norway
Email
  ism@stami.no
Phone
  +47 97114556
Personal website
  stami.no/ansatt/ingrid-sivesind-mehlum
Name of committee
  Regionl Committee for Medical and Health Research Ethics (REC) South East, Norway
Contact Principal Investigator (name)
  Ingrid Sivesind Mehlum
Data access policy (briefly describe)
  Data transfer is not possible. Data access is possible to project participants and collaborating partners and must be approved by the Regional Ethics Committee and register owners.
Is this cohort part of a consortium? (name consortium)
  Not currently (not yet)
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).

Main aim of cohort, please briefly describe the main objectives of the cohort
  To study relations between work-related health and working conditions, work participation and social factors
Study design (please select as many as appropriate)
 

  • Prospective cohort

Source population (please select as many as appropriate)
 

  • General population: National
  • Hospital / patient-based

Comparators (please select as many as appropriate)
 

  • Internal study population

Inclusion criteria
  Total population born 1930-1992, reciding in Norway during 2000-2010
Exclusion criteria
  Died or emigrated before 2000
Enrollment
  Completed
Age range at entry (main cohort)
 

Minimum Maximum Mean
18 (in 2010, i.e. born 1992) 70 (in 2000, i.e. born 1930)

Men at enrollment
  1 988 263
Women at enrollment
  1 909 903
Participation rate at enrollment (if known)
  100
Comments
  Registry-based cohort with anticipated complete follow-up of alive people residing in Norway (excluding those who are dead or emigrated).

Some parts of the form are difficult to fill out for a registry-based cohort - not all questions are relevant, but I have tried to answer most questions.

2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Death certificate
  • Disease incidence records
  • Hospital / physician diagnoses
  • Use of registers (specify)

Death certificate (specify)
 

  • Norwegian Cause of Death Registry

Disease incidence records (specify)
 

  • Norwegian Patient Registry (NPR)

Hospital / Physician diagnoses (specify)
 

  • Norwegian Patient Registry with selected diagnoses (ICD-10) from specialist healthcare in hospitals as well as outpatient treatment.
  • Physician diagnoses from sickness certificates (ICPC-2), and related to disability pension and some other social benefits.

Specify: Use of registers
 

  • Registers from Statistics Norway: Population, Income, Occupation/Employment, Education, Event Database FD-Trygd
  • Norwegian Labour and Welfare Administration: Social benefits diagnoses (Sickness absence, Disability pension, and others)
  • Norwegian Cause of Death Registry
  • Norwegian Patient Registry

First follow-up period (provide year)
  2000
Last follow-up period (provide year)
  2019
Number of follow-ups after baseline (provide number)
  (some data are annual, other event data; last update varies between registers)
Participation at last follow-up (if known)
  100
Comments
  Registry-based cohort with anticipated complete follow-up of alive people residing in Norway (excluding those who are dead or emigrated).
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Job-employment records
  • Registry-based

Occupational history/time frame
  Follow-up period
Occupational coding performed
  Yes
Occupation (specify coding system used)
 

  • ISCO-88 (Norwegian version), annually from 2007

Industry (specify coding system used)
 

  • NACE (Nomenclature des Activités Économiques dans la Communauté Européenne)(event data)

Methods for exposure assessment (please select as many as appropriate)
 

  • Job Exposure Matrix

 

  • Other

Specify: Job Exposure Matrix / Other
  NORJEM (Mechanical and psychosocial exposures)
Website
  https://www.sjweh.fi/show_abstract.php?abstract_id=3774
Main categories
 

  • Ergonomics, physical workload, and injury related
  • Psychosocial domains

Ergonomics, physical workload, and injury related
 

  • Awkward work postures (e.g. kneeling/squatting, elevated arms, neck flection, back bent forward without support)
  • Physical work load (e.g. heavy lifting of people or objects, pushing/pulling)
  • Standing work

Psychosocial domains | Job task characteristics/organization of work
 

  • Job control, autonomy
  • Psychological job demands
  • Social support at work from supervisors
  • Other (specify)

Psychosocial domains | Job task characteristics/organization of work | Specify: Other
  monotonous work
Comments
  8 different mechanical work exposures:
(i) heavy lifting,
(ii) neck flexion,
(iii) hands above shoulder height,
(iv) squatting/kneeling,
(v) forward bending,
(vi) awkward lifting,
(vii) heavy physical work and
(viii) standing/walking.

5 psychosocial exposure dimensions:
(i) psychological demands, consisting of three dimensions: quantitative demands, role conflict and emotional demands;
(ii) decision latitude, consisting of two dimensions: decision authority and skill discretion;
(iii) job strain constructed by combining psychological demands and decision latitude;
(iv) monotonous work measured by a single item; and
(v) supportive leadership measured with three items.

4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Death certificates
  • Medical records
  • Registry-based

Registry-based
 

  • Disease specific clinical database
  • Employment status
  • Hospital discharge
  • Mortality register
  • Migration

Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Death certificates
  • Registry-based

Registry-based
 

  • Disease specific clinical database
  • Employment status
  • Hospital discharge
  • Mortality register
  • Migration

Outcome type (please select as many as appropriate)
 

  • Mortality
  • Morbidity
  • Disability

Diagnostic groups based on ICD10
 

  • E Endocrinological disease
  • E Malnutrition and obesity
  • F Mental disorders
  • G Disease in the nervous system
  • H Disorders of the ear
  • I Heart disease
  • J Respiratory disease
  • L Skin, nail and hair disorders
  • M Arthritis, arthrosis, systemic connective disorders, spine disorders
  • M Disorders of muscles, bones, synovialis, bursa, cartilage
  • O+P Pregnancy and labour
  • S Injuries
  • Other (specify)

Other (specify)
  Other ICD-10 diagnoses: V+Y External causes of morbidity; Z Factors influencing health status and contact with health services
E Endocrinological disease
 

  • Diabetes mellitus

F Mental disorders
 

  • Dementia
  • Personality and behavioural disorders
  • Schizophrenia
  • Mood [affective] disorders
  • Depression
  • Eating disorders
  • Mental retardation
  • Disorders of psychological development including autism and Aspergers syndrome
  • Other mental disorder, not otherwise specified
  • Other, please state

F Mental disorders | Other (specify)
  (all ICD-10 codes in chapter F)
G Disease in the nervous system
 

  • Systemic atrophies primarily affecting the central nervous system including
  • Spinal muscular atrophy and related syndromes
  • Parkinson's disease
  • Alzheimer's disease
  • Multiple sclerosis
  • Migraine
  • Sleep disorders
  • Carpal tunnel syndrome
  • Lesion of ulnar nerve
  • Lesion of radial nerve
  • Other mononeuropathies
  • Polyneuropathies and other disorders of the peripheral nervous system
  • Toxic encephalopathy

H Disorders of the ear
 

  • Diseases of inner ear

I Heart disease
 

  • Hypertensive diseases
  • Angina pectoris
  • Acute myocardial infarction
  • Chronic ischaemic heart disease
  • Other, please state

I Heart disease | Other (specify)
  Other ICD-10 diagnoses: I73.0 Raynaud's syndrome; I83 Varicose veins of lower extremities
J Respiratory disease
 

  • Vasomotor and allergic rhinitis
  • Chronic rhinitis, nasopharyngitis and pharyngitis
  • Chronic Bronchitis
  • Emphysema
  • Chronic obstructive pulmonary disease (COPD)
  • Asthma
  • Byssinosis
  • Bronchiectasis
  • Pneumoconiosis
  • Hypersensitivity pneumonitis due to organic dust
  • Other interstitial lung disease
  • Other, please state

J Respiratory disease | Other (specify)
  J92 Pleural plaque (in ICD-10)
L Skin, nail and hair disorders
 

  • Allergic contact dermatitis
  • Irritant contact dermatitis
  • Psoriasis/Parapsoriasis
  • Urticaria
  • Other, please state

L Skin, nail and hair disorders | Other (specify)
  L25 Unspecified contact dermatitis (ICD-10)
M Arthritis, arthrosis, systemic connective disorders, spine disorders
 

  • Coxarthrosis
  • Gonarthrosis [arthrosis of knee]
  • Spine disk disorders
  • Lumbago with sciatica
  • Low back pain

M Disorders of muscles, bones, synovialis, bursa, cartilage
 

  • Chronic crepitant synovitis of hand and wrist
  • Bursitis of hand
  • Olecranon bursitis
  • Prepatellar bursitis
  • Other bursitis
  • Rotator cuff syndrome
  • Bicipital tendinitis
  • Calcific tendinitis of shoulder
  • Impingement syndrome of shoulder
  • Medial epicondylitis
  • Lateral epicondylitis
  • Other Synovitis and tenosynovitis

O+P Pregnancy and labour
 

  • Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
  • Eclampsia in pregnancy, labour or puerperium
  • Excessive vomiting in pregnancy
  • Venous complications in pregnancy
  • Infections of genito-urinary tract in pregnancy
  • Diabetes mellitus in pregnancy
  • Malnutrition in pregnancy
  • Other specified pregnancy-related conditions
  • Complications of labour and delivery
  • Preterm delivery
  • Extremely low birth weight
  • Other low birth weight
  • Exceptionally large baby
  • Birth trauma
  • Congenital viral diseases
  • Foetal death of unspecified cause
  • Other, please state

O+P Pregnancy and labour | Other (specify)
  All pregnancy-related diagnoses that lead to sickness absence (ICPC-2 diagnoses: W)
S Injuries
 

  • Injuries to the head
  • Injuries to the thorax
  • Injuries to the abdomen, lower back, lumbar spine and pelvis
  • Injuries to the shoulder, arm and fingers
  • Injuries to the hip and thigh
  • Injuries to the knee and lower leg, ankle and foot
  • Other, please state

S Injuries | Other (specify)
  All ICD-10 diagnoses S00-T98
Other health related outcomes
 

  • Sickness absence
  • Work participation
  • Other (specify)

Specify: Other
  Disability pension
Comments
  Additional ICD--10 diagnoses:
All codes V+Y External causes of morbidity (V00 - Y99)

Z Factors influencing health status and contact with health services:
- Z56 Problems related to employment and unemployment
- Z57 Occupational exposure to risk factors

The diagnoses indicated (except pregnancy-related diagnoses) are the ones we have requested from the Norwegian Patient Registry (NPR), as they are potentially work-related.
We were not allowed to get all diagnoses in NPR, we had to request specific diagnoses and argue why they were necessary for our project, and get approval from REC and NPR.

We also have other diagnoses:
- Mortality diagnoses from the Norwegian Cause of Death Registry
- All diagnoses related to Sickness absence (ICPC-2 codes), Disability pension and other social benefits

5. BIOLOGICAL SAMPLES & ANALYSIS
Comments
  No biological samples
6. Other Information
 

  • Demographics
  • Education
  • Residential history
  • Socioeconomic status

Possibility for linkage to data registries/data enrichment via data linkage
 

  • Cancer incidence
  • Medication usage

Please describe plans that are funded or most likely to be funded
  We plan to update some of the data, including additional diagnoses from NPR, particularly if the data can be used in a Covid-19 project.

We also plan to supplement the population, including everyone born 1930-92 who have resided or worked in Norway.

We also plan to include data from other registers:
- The Cancer Registry of Norway
- The Prescription Database
- Censuses (1960, 1970, 1980, 1990) to get data on previous occupations (coded in NYK, based on ISCO-58)

We have previously included immigrants who lived in Norway 2000-2010, but also want to include more recent immigrants when we are going to update the data.