Date of filling in this questionnaire or last update: 09/11/2021
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  INUENDO
Country
 

  • Albania
  • Greenland
  • Poland
  • Sweden
  • Ukraine

Name
  Gunnar Toft
Institution
  Aarhus University Hospital
Email
  guntof@rm.dk
Upload files
 

Contact Principal Investigator (name)
  Gunnar Toft
Data access policy (briefly describe)
  Approval from all data collecting centers and data transfer agreeement is needed
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).

Main aim of cohort, please briefly describe the main objectives of the cohort
  To study the effects of exposure to persistent organic pollutants on male and female fertility
Study design (please select as many as appropriate)
 

  • Prospective cohort

Source population (please select as many as appropriate)
 

  • General population: International
  • Mother-child cohort

Comparators (please select as many as appropriate)
 

  • Internal study population

Inclusion criteria
  Pregnant women, >18 years of age, + husbands/spouses
Enrollment
  Completed
Age range at entry (main cohort)
 

Minimum Maximum Mean
18 64 30

Men at enrollment
  797
Women at enrollment
  2269
Children (<18 years) at enrollment
  0
Children (<18 years) at last follow-up
  1109
Participation rate at enrollment (if known)
  43
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Active (contact with participants)

Active (contact with participants) (specify)
 

  • Follow up on childhood growth and development at 6-9 years of age

3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Questionnaire, Personal (Self-reporting or interview)
  • Questionnaire, Personal (Occupational/industry modules)
  • Industry-based questionnaire

Occupational history/time frame
  Current, at enrollment
Occupational coding performed
  Yes
Occupation (specify coding system used)
 

  • ISCO

Industry (specify coding system used)
 

  • NACE

Methods for exposure assessment (please select as many as appropriate)
 

  • Self-report

Main categories
 

  • Pesticides
  • Metals and metal oxides
  • Other chemicals

Pesticides | Insecticides
 

  • DDT

Metals and metal oxides
 

  • Cadmium and all compounds
  • Lead and all compounds
  • Mercury, organic, inorganic

Other chemicals | Flame retardants
 

  • Flame retardants

Other chemicals | Per- and polyfluoroalkyl substances (PFAS)
 

  • Per- and polyfluoroalkyl substances (PFAS)

Other chemicals | Phthalates
 

  • Phthalates

Other chemicals | PCBs
 

  • PCBs (polychlorinated biphenyls)

4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Questionnaire, individual (self-recording or interview)

Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Questionnaire, individual (self-recording or interview)

Outcome type (please select as many as appropriate)
 

  • Morbidity
  • Disability

Diagnostic groups based on ICD10
 

  • E Malnutrition and obesity
  • F Mental disorders
  • N Male and female related disorders
  • O+P Pregnancy and labour
  • Q After birth – child disorders

E Malnutrition and obesity
 

  • Obesity

F Mental disorders
 

  • Personality and behavioural disorders
  • Disorders of psychological development including autism and Aspergers syndrome

N Male and female related disorders
 

  • Male infertility
  • Abnormal menstrual cycle
  • Female infertility
  • Spontaneous abortion

O+P Pregnancy and labour
 

  • Preterm delivery
  • Other low birth weight
  • Exceptionally large baby

5. BIOLOGICAL SAMPLES & ANALYSIS
Biological samples collected
 

  • Blood
  • Other

Specify: Other
  Buccal swabs
Biological processing
 

  • DNA

6. Other Information
 

  • Alcohol
  • Anthropometry
  • Demographics
  • Diet
  • Education
  • Environmental other (specify)
  • Medical history
  • Socioeconomic status
  • Smoking

Specify: Environmental other
  Biomarker measurements of environmental exposures as previously pecified