Date of filling in this questionnaire or last update: 02/11/2021
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  Mexico City Prospective Study
Country
 

  • Mexico

Please provide any other information on the cohort location/s if needed
  Mexico City
Name
  Roberto Tapia-Conyer
Institution
  National Autonomous University of Mexico
Email
  mcps-access@ndph.ox.ac.uk
Name
  Jonathan Emberson
Institution
  University of Oxford
Email
  mcps-access@ndph.ox.ac.uk
Website
 

  • https://www.ctsu.ox.ac.uk/research/prospective-blood-based-study-of-150-000-individuals-in-mexico

Name of committee
  Mexican Ministry of Health; Mexican National Council for Science and Technology; University of Oxford
Upload files
 

Contact Principal Investigator (name)
  Jonathan Emberson
Data access policy (briefly describe)
  We welcome requests from researchers who wish to access data from the Mexico City Prospective Study. If you are interested in obtaining data from the study for research purposes, or in collaborating with us on a specific research proposal, please visit our study website [https://www.ctsu. ox.ac.uk/research/prospective-blood-based-study-of-150- 000-individuals-in-mexico] where you can download our Data and Sample Access Policy in either English or Spanish.
Is this cohort part of a consortium? (name consortium)
  No
Main aim of cohort, please briefly describe the main objectives of the cohort
  To study the major social, lifestyle, physical, metabolic and genetic causes of disease in Mexican adults
Study design (please select as many as appropriate)
 

  • Prospective cohort

Source population (please select as many as appropriate)
 

  • General population: Regional

Comparators (please select as many as appropriate)
 

  • Internal study population

Inclusion criteria
  Age 35 years or older from two districts of Mexico City
Exclusion criteria
  None
Enrollment
  Completed
Age range at entry (main cohort)
 

Minimum Maximum Mean
35 No upper age limit

Men at enrollment
  ~50,000
Women at enrollment
  ~100,000
Children (<18 years) at enrollment
  0
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Death certificate

First follow-up period (provide year)
  1998
Last follow-up period (provide year)
  2018
Number of follow-ups after baseline (provide number)
  1
Participation at last follow-up (if known)
  7
Comments
  Between 2015-2019 a resurvey of 10,000 survivors was completed.
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Questionnaire, Personal (Self-reporting or interview)

Occupational history/time frame
  Current, at enrollment
Occupational coding performed
  No
Types of exposure measurements
 

  • Other (specify)

Specify: Other
  Questionnaire data, physical measurements and blood biomarkers
Methods for exposure assessment (please select as many as appropriate)
 

  • Measurements (external sampling, biomarkers)
  • Self-report

Main categories
 

  • Other (specify)

Main categories | Other | Specify: Other
  None
4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Biomarker (specify)
  • Questionnaire, individual (self-recording or interview)

Specify: Biomarker
  A range of blood biomarkers
Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Death certificates

Outcome type (please select as many as appropriate)
 

  • Mortality

Diagnostic groups based on ICD10
 

  • Other (specify)

Other (specify)
  Death certificates are coded according to ICD-10
5. BIOLOGICAL SAMPLES & ANALYSIS
Biological samples collected
 

  • Blood

Biological processing
 

  • DNA

Genetic and other lab analyses
 

  • Biomarkers (specify)
  • Genomics / GWAS
  • Genomics / Other genetics (specify)
  • Metabolomics

Specify: Biomarkers
  A range of blood biomarkers have been measured.
Specify: Other genetics
  Exome sequence data
6. Other Information
 

  • Alcohol
  • Anthropometry
  • Demographics
  • Diet
  • Education
  • Medical history
  • Physical exercise
  • Socioeconomic status
  • Smoking