Date of filling in this questionnaire or last update: 20/06/2021
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  ATOHS
Country
 

  • Sweden

Please provide any other information on the cohort location/s if needed
  Stockholm
Name
  Per Gustavsson
Institution
  Karolinska Institutet
Email
  per.gustavsson@ki.se
Phone
  +46739017844
Personal website
  https://staff.ki.se/people/pergus
Name of committee
  Regional Ethics Review Board, Stockholm
Contact Principal Investigator (name)
  Per Gustavsson
Data access policy (briefly describe)
  De-identified data potentially available
Is this cohort part of a consortium? (name consortium)
  No
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).

Main aim of cohort, please briefly describe the main objectives of the cohort
  Investigate the effects of night work and shift work on risks of cancer, cardiovascular disease, pregnancy outcome, and psychological diseases/diagnoses
Study design (please select as many as appropriate)
 

  • Prospective cohort
  • Retrospective cohort

Source population (please select as many as appropriate)
 

  • Other

Specify: Other
  Health care workers in Stockholm
Comparators (please select as many as appropriate)
 

  • Internal study population

Inclusion criteria
  All employed >1 year 2008-2017
Enrollment
  Completed
Men at enrollment
  15000
Women at enrollment
  45000
Children (<18 years) at enrollment
  0
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Disease incidence records
  • Hospital / physician diagnoses
  • Use of registers (specify)

Disease incidence records (specify)
 

  • Death, cancer, Birth outcome, CVD

Hospital / Physician diagnoses (specify)
 

  • cancer, Birth outcome, CVD

Specify: Use of registers
 

  • National registers

First follow-up period (provide year)
  2008
Last follow-up period (provide year)
  2016
Comments
  Note: there is no personal identification in the cohort after matching to central registers. It is not possible to add more data from other registers.  
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Job-employment records
  • Registry-based

Occupational history/time frame
  Follow-up period
Occupational coding performed
  No
Methods for exposure assessment (please select as many as appropriate)
 

  • Other (specify)

Specify: Other
  Registry based
Main categories
 

  • Organisation of work including working time

Organisation of work including working time | Shift work
 

  • Night (permanent or rotating)
  • Regular/variable

Organisation of work including working time | Working hours
 

  • Duration
  • Regular/variable

Comments
  Detailed data on working hours day-by day for entire study period
4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Registry-based

Registry-based
 

  • Birth register
  • Cancer incidence
  • Hospital discharge
  • Medication usage
  • Mortality register

Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Registry-based

Diagnostic groups based on ICD10
 

  • C + D Neoplasms
  • F Mental disorders
  • I Heart disease
  • I Cerebrovascular diseases
  • O+P Pregnancy and labour

C + D Neoplasms
 

  • Malignant neoplasm of breast
  • Malignant neoplasms of male genital organs

F Mental disorders
 

  • Depression

I Heart disease
 

  • Acute myocardial infarction

I Cerebrovascular diseases
 

  • Subarachnoid haemorrhage
  • Intracerebral haemorrhage
  • Cerebral infarction
  • Stroke, not specified as haemorrhage or infarction

O+P Pregnancy and labour
 

  • Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
  • Eclampsia in pregnancy, labour or puerperium
  • Preterm delivery
  • Extremely low birth weight
  • Other low birth weight

6. Other Information
 

  • Socioeconomic status

Please describe plans that are funded or most likely to be funded
  Updates and addition of new employees are planned