Date of filling in this questionnaire or last update: 22/10/2020
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  West of Scotland Twenty-07 Study
Country
 

  • United Kingdom

Please provide any other information on the cohort location/s if needed
  Scotland, United Kingdom
Name
  Elise Whitley
Institution
  University of Glasgow
Email
  sphsu-twenty07@glasgow.ac.uk
Phone
  +44 141 353 7500
Personal website
  https://www.gla.ac.uk/researchinstitutes/healthwellbeing/staff/elisewhitley/
Website
 

  • http://2007study.sphsu.mrc.ac.uk/

Name of committee
  National Health Service or University of Glasgow ethics committee approval was obtained for each wave of the study . For Wave 5, NHS Tayside Committee on Medical Research Ethics A
Or provide website
 

  • Cohort profile: https://academic.oup.com/ije/article/38/5/1215/663256
  • Questionnaires: http://2007study.sphsu.mrc.ac.uk/Interview-Schedules.html
  • Publications: http://2007study.sphsu.mrc.ac.uk/Publications.html

Data access policy (briefly describe)
  We are committed to maximizing the use of Twenty-07 data to advance knowledge to improve human health and welcome proposals for collaborative projects and data sharing. Our data sharing policy aims to balance making data as widely and freely available as possible with safeguarding the privacy of participants, protecting confidential data, and maintaining the reputation of the study. http://2007study.sphsu.mrc.ac.uk/Information-on-data-sharing.html
Is this cohort part of a consortium? (name consortium)
  No
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).

Main aim of cohort, please briefly describe the main objectives of the cohort
  The Twenty-07 Study was set up in 1986 in order to investigate the reasons for differences in health by socio-economic circumstances, gender, area of residence, age, ethnic group, and family type.
Study design (please select as many as appropriate)
 

  • Prospective cohort

Source population (please select as many as appropriate)
 

  • General population: National
  • General population: Regional

Inclusion criteria
  Aged about 15, 35 or 55 in 1987 and living in the Central Clydeside Conurbation
Exclusion criteria
  Not aged about 15, 35, or 55 and not living in the Central Clydeside Conurbation
Enrollment
  Completed
Age range at entry (main cohort)
 

Minimum Maximum Mean
15 58 36

Age range at entry (subcohort)
 

Minimum Maximum Mean Please describe
15 16 15 Youth cohort
31 42 36 Mid thirties cohort
54 58 56 Mid life cohort

Men at enrollment
  1358
Women at enrollment
  1637
Children (<18 years) at enrollment
  1515
Men at last follow-up
  1160
Women at last follow-up
  1444
Children (<18 years) at last follow-up
  0
Participation rate at enrollment (if known)
  87
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Active (contact with participants)
  • Death certificate

Active (contact with participants) (specify)
 

  • At each interview, participants were asked detailed health questions

Death certificate (specify)
 

  • All participants are flagged at the NHS Central Register in Scotland and we get sent date and cause of death

First follow-up period (provide year)
  1987 (baseline)
Last follow-up period (provide year)
  2007
Number of follow-ups after baseline (provide number)
  4
Participation at last follow-up (if known)
  58
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Questionnaire, Personal (Self-reporting or interview)
  • Job calendar

Occupational history/time frame
  Other (specify)
Specify: Other
  Sort of all of these. We asked about current, then at each follow up, and sometimes about main lifetime job.
Occupational coding performed
  Yes
Occupation (specify coding system used)
 

  • SOC90

Types of exposure measurements
 

  • Biomarkers (see also section 5)

Methods for exposure assessment (please select as many as appropriate)
 

  • Self-report

Main categories
 

  • Ergonomics, physical workload, and injury related

Ergonomics, physical workload, and injury related
 

  • Physical work load (e.g. heavy lifting of people or objects, pushing/pulling)
  • Sedentary work
  • Standing work

4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
  • Questionnaire, individual (self-recording or interview)

Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
  respiratory function, blood pressure, other physical measures
Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Biomarker (specify)
  • Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
  • Death certificates
  • Questionnaire, individual (self-recording or interview)

Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
  respiratory function, blood pressure, other physical measures
Specify: Biomarker
  Some blood results available at final follow up.
Outcome type (please select as many as appropriate)
 

  • Mortality
  • Morbidity
  • Disability

Diagnostic groups based on ICD10
 

  • Other (specify)

Other (specify)
  From death certificates we have cause of death so we can get major causes such as heart disease , respiratory, cancer.
Other health related outcomes
 

  • Biomarkers
  • Lifestyle change
  • Quality of life/wellbeing
  • Sleep
  • Work participation

5. BIOLOGICAL SAMPLES & ANALYSIS
Biological samples collected
 

  • Blood

Biological processing
 

  • DNA

Genetic and other lab analyses
 

  • Other (specify)

Specify: Other
  We have telomere length.
6. Other Information
 

  • Alcohol
  • Anthropometry
  • Demographics
  • Diet
  • Education
  • Environmental other (specify)
  • Medical history
  • Physical exercise
  • Residential history
  • Socioeconomic status
  • Smoking

Specify: Environmental other
  postcode could be used to assess other environmental factors
Possibility for linkage to data registries/data enrichment via data linkage
 

  • Hospital discharge
  • Mortality register

Please describe plans that are funded or most likely to be funded
  Only plan to continue with mortality flagging. Data linkage to hospital discharge could happen if funding was applied for. There is consent for this.