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Date of filling in this questionnaire or last update: 25/09/2024
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  Norwegian 1967-1976 Birth Cohort
Country
 

  • Norway
Please provide any other information on the cohort location/s if needed
  All live-born in Norway between 1967-1976, registry-based
Name
  Karl-Christian Nordby
Institution
  STAMI (National Institute of Occupational Health, Oslo Norway)
Email
  karl.c.nordby@stami.no
Name of committee
  Regional Committee for Medical and Health Research Ethics (REC) South East, Norway
Upload files
 

Contact Principal Investigator (name)
  Karl-Christian Nordby
Data access policy (briefly describe)
  Data transfer is not possible. Data access is possible to project participants and collaborating partners and must be approved by the Regional Ethics Committee and register owners.
Is this cohort part of a consortium? (name consortium)
  EPHOR
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
Main aim of cohort, please briefly describe the main objectives of the cohort
  To study relations between work-related health and working conditions, work participation and social factors in a life-course perspective, including data about childhood conditions and parents.
Study design (please select as many as appropriate)
 

  • Prospective cohort
Source population (please select as many as appropriate)
 

  • General population: National
  • Generation (parents-children) study
Comparators (please select as many as appropriate)
 

  • Internal study population
Inclusion criteria
  Total population live-born in Norway 1967-1976, and their parents
Exclusion criteria
  None
Enrollment
  Completed
Age range at entry (main cohort)
 

Minimum Maximum Mean
26 yrs in 2002 (born 1976) 35 yrs in 2002 (born 1967)

Men at enrollment
  321975
Women at enrollment
  304953
Participation rate at enrollment (if known)
  100
Comments
  Registry-based cohort comprising the total population born in Norway 1967-1976 (N = 626 928 individuals), and their parents
Norwegian national registers are considered to be complete.
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Death certificate
  • Disease incidence records
  • Hospital / physician diagnoses
  • Use of registers (specify)
Death certificate (specify)
 

  • Norwegian Cause of Death Registry
Disease incidence records (specify)
 

  • Cancer Registry of Norway, Norwegian Patient Registry
Hospital / Physician diagnoses (specify)
 

  • Norwegian Patient Registry with diagnoses (ICD-10) from specialist healthcare in hospitals as well as outpatient treatments.
  • Physician diagnoses from sickness certificates (ICPC-2), and related to disability pension and some other social benefits.
Specify: Use of registers
 

  • Registers from Statistics Norway: Population , Income, Employment/Occupation, Education, Event Database FD-Trygd
  • Norwegian Labour and Welfare Administration: Social benefits diagnoses (Sickness absence, Disability pension, and others)
  • Norwegian Cause of Death Registry, Cancer Registry of Norway, Norwegian Patient Registry
  • Norwegian Armed Forces Personnel Data Base
First follow-up period (provide year)
  1967
Last follow-up period (provide year)
  2022
Participation at last follow-up (if known)
  100
Comments
  Registry-based cohort with no loss to follow-up.
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Job-employment records
  • Registry-based
Occupational history/time frame
  Follow-up period
Occupational coding performed
  Yes
Occupation (specify coding system used)
 

  • ISCO-88 (Norwegian version), annually from 2003.
Industry (specify coding system used)
 

  • NACE (Nomenclature des Activités Économiques dans la Communauté Européenne), from 1995 (event data)
Methods for exposure assessment (please select as many as appropriate)
 

  • Job Exposure Matrix
 

  • Other
Specify: Job Exposure Matrix / Other
  NORJEM (Mechanical and psychosocial exposures)
Website
  https://www.sjweh.fi/show_abstract.php?abstract_id=3774
Main categories
 

  • Ergonomics, physical workload, and injury related
  • Psychosocial domains
Ergonomics, physical workload, and injury related
 

  • Awkward work postures (e.g. kneeling/squatting, elevated arms, neck flection, back bent forward without support)
  • Physical work load (e.g. heavy lifting of people or objects, pushing/pulling)
  • Standing work
Psychosocial domains | Job task characteristics/organization of work
 

  • Job control, autonomy
  • Psychological job demands
  • Social support at work from supervisors
  • Skill use opportunities
  • Other (specify)
Psychosocial domains | Job task characteristics/organization of work | Specify: Other
  Monotonous work
Comments
  8 different mechanical work exposures:
(i) heavy lifting,
(ii) neck flexion,
(iii) hands above shoulder height,
(iv) squatting/kneeling,
(v) forward bending,
(vi) awkward lifting,
(vii) heavy physical work and
(viii) standing/walking.

5 psychosocial exposure dimensions:
(i) psychological demands, consisting of three dimensions: quantitative demands, role conflict and emotional demands;
(ii) decision latitude, consisting of two dimensions: decision authority and skill discretion;
(iii) job strain constructed by combining psychological demands and decision latitude;
(iv) monotonous work measured by a single item; and
(v) supportive leadership measured with three items.

4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Death certificates
  • Medical records
  • Registry-based
Registry-based
 

  • Birth register
  • Cancer incidence
  • Disease specific clinical database
  • Employment status
  • Mortality register
  • Other
Specify: Other
  Diagnoses related to social benefits (sickness absence, disability pension, and others, incl. benefits related to health conditions in childhood and adolescence)
Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Death certificates
  • Medical records
  • Registry-based
Registry-based
 

  • Cancer incidence
  • Disease specific clinical database
  • Employment status
  • Hospital discharge
  • Mortality register
  • Other
Specify: Other
  Diagnoses related to social benefits (sickness absence, disability pension and others)
Outcome type (please select as many as appropriate)
 

  • Mortality
  • Morbidity
  • Disability
Diagnostic groups based on ICD10
 

  • C + D Neoplasms
  • E Endocrinological disease
  • E Malnutrition and obesity
  • F Mental disorders
  • G Disease in the nervous system
  • H Disorders of the ear
  • I Heart disease
  • J Respiratory disease
  • L Skin, nail and hair disorders
  • M Arthritis, arthrosis, systemic connective disorders, spine disorders
  • M Disorders of muscles, bones, synovialis, bursa, cartilage
  • S Injuries
  • Other (specify)
Other (specify)
  Other ICD-10 diagnoses: V00-Y99 External causes of morbidity, Z00-Z99 Factors influencing health status and contact with health services
C + D Neoplasms
 

  • Benign neoplasm
  • Carcinoma in situ
  • Leukemia
  • Malignant neoplasms gastro intes. system including liver, gall bladder, pancreas
  • Malignant neoplasm lung
  • Mesothelioma
  • Other malignant neoplasm of respiratory and intrathoracic organs, heart, pleura
  • Malignant neoplasm of bone and articular cartilage
  • Melanoma and other malignant neoplasms of skin
  • Neoplasms connective and soft tissue including nerves
  • Malignant neoplasm of breast
  • Malignant neoplasms, females gynecological
  • Malignant neoplasms of male genital organs
  • Malignant neoplasm of urinary tract and kidney
  • Malignant neoplasms of eye, brain and other parts of central nervous system
  • Malignant neoplasms of thyroid and other endocrine glands
  • Malignant neoplasms of ill-defined, secondary and unspecified sites
  • Malignant neoplasm without specification of site including excl. leukemia
  • Other, please state
E Endocrinological disease
 

  • Diabetes mellitus
F Mental disorders
 

  • Dementia
  • Personality and behavioural disorders
  • Schizophrenia
  • Mood [affective] disorders
  • Depression
  • Eating disorders
  • Mental retardation
  • Disorders of psychological development including autism and Aspergers syndrome
  • Other mental disorder, not otherwise specified
  • Other, please state
F Mental disorders | Other (specify)
  (all ICD-10 codes in chapter F)
G Disease in the nervous system
 

  • Systemic atrophies primarily affecting the central nervous system including
  • Spinal muscular atrophy and related syndromes
  • Parkinson's disease
  • Alzheimer's disease
  • Multiple sclerosis
  • Migraine
  • Sleep disorders
  • Carpal tunnel syndrome
  • Lesion of ulnar nerve
  • Lesion of radial nerve
  • Other mononeuropathies
  • Polyneuropathies and other disorders of the peripheral nervous system
  • Toxic encephalopathy
H Disorders of the ear
 

  • Diseases of inner ear
I Heart disease
 

  • Hypertensive diseases
  • Angina pectoris
  • Acute myocardial infarction
  • Chronic ischaemic heart disease
  • Other, please state
I Heart disease | Other (specify)
  Other ICD-10 diagnoses: I73.0 Raynaud's syndrome, I83 Varicose veins of lower extremities
J Respiratory disease
 

  • Vasomotor and allergic rhinitis
  • Chronic rhinitis, nasopharyngitis and pharyngitis
  • Chronic Bronchitis
  • Emphysema
  • Chronic obstructive pulmonary disease (COPD)
  • Asthma
  • Byssinosis
  • Bronchiectasis
  • Pneumoconiosis
  • Hypersensitivity pneumonitis due to organic dust
  • Other interstitial lung disease
  • Other, please state
J Respiratory disease | Other (specify)
  J92 Pleural plaque (in ICD-10)
L Skin, nail and hair disorders
 

  • Allergic contact dermatitis
  • Irritant contact dermatitis
  • Psoriasis/Parapsoriasis
  • Urticaria
  • Other, please state
L Skin, nail and hair disorders | Other (specify)
  L25 Unspecified contact dermatitis (ICD-10)
M Arthritis, arthrosis, systemic connective disorders, spine disorders
 

  • Coxarthrosis
  • Gonarthrosis [arthrosis of knee]
  • Spine disk disorders
  • Lumbago with sciatica
  • Low back pain
M Disorders of muscles, bones, synovialis, bursa, cartilage
 

  • Chronic crepitant synovitis of hand and wrist
  • Bursitis of hand
  • Olecranon bursitis
  • Prepatellar bursitis
  • Other bursitis
  • Rotator cuff syndrome
  • Bicipital tendinitis
  • Calcific tendinitis of shoulder
  • Impingement syndrome of shoulder
  • Medial epicondylitis
  • Lateral epicondylitis
  • Other Synovitis and tenosynovitis
S Injuries
 

  • Injuries to the head
  • Injuries to the thorax
  • Injuries to the abdomen, lower back, lumbar spine and pelvis
  • Injuries to the shoulder, arm and fingers
  • Injuries to the hip and thigh
  • Injuries to the knee and lower leg, ankle and foot
  • Other, please state
S Injuries | Other (specify)
  All ICD-10 diagnoses S00-T98
Other health related outcomes
 

  • Sickness absence
  • Work participation
  • Other (specify)
Specify: Other
  Disability pension
Comments
  Additional ICD-10 codes:
Z56 Problems related to employment and unemployment
Z57 Occupational exposure to risk factors

We also have other diagnoses:
- Cancer diagnoses from the Cancer Registry
- Mortality diagnoses from the Norwegian Cause of Death Registry
- All diagnoses related to Sickness absence (ICPC-2 codes), Disability pension and other social benefits

6. Other Information
 

  • Anthropometry
  • Demographics
  • Education
  • Residential history
  • Socioeconomic status
  • Other (specify)
Specify: Other
  Cognitive ability and anthropometry at conscription (mostly males, at approx. 18 yrs.)