| 1. IDENTIFICATION & BASIC DESCRIPTION |
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Cohort name
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SkinWork
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Country
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Name
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Jelena Macan
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Institution
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Institute for Medical Research and Occupational Health, Zagreb
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Email
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jmacan@imi.hr
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Name
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Zrinka Franić
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Institution
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Institute for Medical Research and Occupational Health, Zagreb
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Email
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zfranic@imi.hr
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Name of committee
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Ethical Committee of the Institute for Medical Research and Occupational Health, Zagreb; Ethical Committee of the School of Medicine, University of Zagreb
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Contact Principal Investigator (name)
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Jelena Macan
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Is this cohort part of a consortium? (name consortium)
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No
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Participation in pooled analyses
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- The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
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Main aim of cohort, please briefly describe the main objectives of the cohort
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A cohort of hairdressing apprentices followed up to establish incidence of occupational skin diseases during apprenticeship, and constitutional/environmental protective/risk factors interactions
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Comparators (please select as many as appropriate)
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- Internal study population
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Inclusion criteria
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signed informed consent; hairdressing apprentices
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Exclusion criteria
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without signed informed consent
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Enrollment
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Ongoing
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Age range at entry (main cohort)
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| Minimum |
Maximum |
Mean |
| 14 |
17 |
15 |
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Men at enrollment
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18
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Women at enrollment
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334
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Children (<18 years) at enrollment
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352
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Participation rate at enrollment (if known)
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64
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| 2. OUTCOME FOLLOW-UP |
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Type of data for outcome follow-up (please select as many as appropriate)
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- Active (contact with participants)
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Active (contact with participants) (specify)
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- active examination of apprentices in schools
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First follow-up period (provide year)
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2018
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Last follow-up period (provide year)
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2020
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Number of follow-ups after baseline (provide number)
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3
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| 3. OCCUPATIONAL EXPOSURES |
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Source of exposure data collected (please select as many as appropriate)
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- Questionnaire, Personal (Self-reporting or interview)
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Occupational history/time frame
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Follow-up period
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Occupational coding performed
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No
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Industry (specify coding system used)
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Types of exposure measurements
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Specify: Other
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frequency of exposure to specific working tasks during practical training
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Methods for exposure assessment (please select as many as appropriate)
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Main categories
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Other chemicals | Detergents and cleaning products
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Other chemicals | Other
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Other chemicals | Other | Specify: Other
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hairdressing chemicals (hair dyes, chemicals for curling hair, shaping hair etc.)
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| 4. OUTCOMES EVALUATED |
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Baseline - type of outcome data collected (select more than one if applicable)
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- Biomarker (specify)
- Questionnaire, individual (self-recording or interview)
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Specify: Biomarker
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filagrrin gene polimorphisms (2282del4, R501X), TNFalpha-308G>A polymorphism
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Follow-up - type of outcome data collected (select more than one if applicable)
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- Questionnaire, individual (self-recording or interview)
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Outcome type (please select as many as appropriate)
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Diagnostic groups based on ICD10
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- L Skin, nail and hair disorders
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L Skin, nail and hair disorders
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- Atopic dermatitis
- Allergic contact dermatitis
- Irritant contact dermatitis
- Urticaria
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Other health related outcomes
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| 5. BIOLOGICAL SAMPLES & ANALYSIS |
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Biological samples collected
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Specify: Other
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buccal swabs
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Biological processing
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Genetic and other lab analyses
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Specify: Biomarkers
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filaggrin gene polymotphisms 2282del4, R501X; TNFalpha-308G-A polymorphism
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| 6. Other Information |
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- Education
- Environmental other (specify)
- Medical history
- Smoking
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Specify: Environmental other
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self-reported data on non-occupational exposure to skin hazards
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Possibility for linkage to data registries/data enrichment via data linkage
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- Disease specific clinical database
- Employment status
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Please describe plans that are funded or most likely to be funded
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Collection of data in this cohort will be finished this year.
We plan to form a new cohort of apprentice nurses, beginning this autumn with similar methodology
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