Date of filling in this questionnaire or last update: 04/08/2020
1. IDENTIFICATION & BASIC DESCRIPTION
Cohort name
  Danish Wood Dust Cohort
Country
 

  • Denmark

Name
  Vivi Schlünssen
Institution
  Aarhus University
Email
  vs@ph.au.dk
Phone
  +45 28992499
Personal website
  http://au.dk/da/vs@ph
Name of committee
  Ethics Committee for Viborg County, Denmark.
Upload files
 

Contact Principal Investigator (name)
  Vivi Schlünssen
Is this cohort part of a consortium? (name consortium)
  No
Participation in pooled analyses
 

  • The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).

Main aim of cohort, please briefly describe the main objectives of the cohort
  The main aim of the cohort is to investigate respiratory health effect of wood dust exposure. A second aim is to identify determinants for wood dust exposure
Study design (please select as many as appropriate)
 

  • Prospective cohort

Source population (please select as many as appropriate)
 

  • Industry / occupation-based

Comparators (please select as many as appropriate)
 

  • Internal study population
  • External comparison of workers with other exposure

Inclusion criteria
  Furniture factories in a specifieWorkers employed in the woodworking, assembly and stock departments of furniture factories in former Voborg county, Denmark
Enrollment
  Completed
Age range at entry (main cohort)
 

Minimum Maximum Mean
16 67 36

Men at enrollment
  1665
Women at enrollment
  368
Men at last follow-up
  1137
Women at last follow-up
  240
Participation rate at enrollment (if known)
  88
2. OUTCOME FOLLOW-UP
Type of data for outcome follow-up (please select as many as appropriate)
 

  • Active (contact with participants)

First follow-up period (provide year)
  2003-4
Last follow-up period (provide year)
  2003-4
Number of follow-ups after baseline (provide number)
  1
Participation at last follow-up (if known)
  68
Comments
  It is posible to followup the cohort in Danish registerts (e.g. ISCO codes and NACE codes for occupation, hospital diagnosis, medication)
3. OCCUPATIONAL EXPOSURES
Source of exposure data collected (please select as many as appropriate)
 

  • Questionnaire, Personal (Occupational/industry modules)
  • Industry-based questionnaire
  • Environmental samples

Occupational history/time frame
  Lifetime
Occupational coding performed
  Yes
Industry (specify coding system used)
 

  • NACE rev2

Types of exposure measurements
 

  • Personal external sampling

Methods for exposure assessment (please select as many as appropriate)
 

  • Data modelling
  • Job Exposure Matrix
  • Measurements (external sampling, biomarkers)

 

  • Other

Specify: Job Exposure Matrix / Other
  Internal job exposure matrix based on measurements, factory size and job task. jacobsen et al Eur Respir J 2009; 33: 1268–1276
Main categories
 

  • Dusts and fibres
  • Solvents

Dusts and fibres | Organic dusts
 

  • Wood dust (not specified)

Solvents | Aliphatic and alicyclic hydrocarbon solvents
 

  • Other (specify)

Solvents | Aliphatic and alicyclic hydrocarbon solvents | Specify: Other
  Turpenes
4. OUTCOMES EVALUATED
Baseline - type of outcome data collected (select more than one if applicable)
 

  • Biomarker (specify)
  • Clinical/functional evaluation, e.g. spirometry, ECGs (specify)
  • Questionnaire, individual (self-recording or interview)

Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
  pre- and post shift Spirometry (all), skin prick test PEF and BHR (a subsample)
Follow-up - type of outcome data collected (select more than one if applicable)
 

  • Biomarker (specify)
  • Clinical/functional evaluation, e.g. spirometry, ECGs (specify)

Specify: Clinical/functional evaluation, e.g. spirometry, ECGs
  spirometry
Specify: Biomarker
  Specific IgE
Outcome type (please select as many as appropriate)
 

  • Morbidity

Diagnostic groups based on ICD10
 

  • J Respiratory disease
  • L Skin, nail and hair disorders

J Respiratory disease
 

  • Vasomotor and allergic rhinitis
  • Chronic Bronchitis
  • Chronic obstructive pulmonary disease (COPD)
  • Asthma

L Skin, nail and hair disorders
 

  • Atopic dermatitis
  • Allergic contact dermatitis
  • Irritant contact dermatitis

5. BIOLOGICAL SAMPLES & ANALYSIS
Biological samples collected
 

  • Blood

Biological processing
 

  • DNA

Genetic and other lab analyses
 

  • Biomarkers (specify)
  • Genomics / GWAS

Specify: Biomarkers
  Specific IgE at follow up. DNA and GWAS on a subsample (Included in the EU project GABRIEL, Moffatt et al NEJM 2010;363:1211-21)
6. Other Information
 

  • Anthropometry
  • Demographics
  • Education
  • Medical history
  • Socioeconomic status
  • Smoking

Possibility for linkage to data registries/data enrichment via data linkage
 

  • Birth register
  • Cancer incidence
  • Disease specific clinical database
  • Employment status
  • Hospital discharge
  • Medication usage
  • Migration
  • Mortality register
  • Other (specify)

Specify: Other
  enrironmental exposure (e.g. air pollution, drinking water quality
Please describe plans that are funded or most likely to be funded
  No current plans