2020

1. IDENTIFICATION & BASIC DESCRIPTION Cohort name   UK Biobank Country   United Kingdom Please provide any other information on the cohort location/s if needed   National survey, England and Wales Name   Rory Collins Institution   University of Oxford Email   rory.collins@ndph.ox.ac.uk Website   https://www.ukbiobank.ac.uk/ Name of committee   Multiple Or provide website   https://www.ukbiobank.ac.uk/key-documents/ Data access policy (briefly describe)   http://www.ukbiobank.ac.uk/wp-content/uploads/2012/09/Access-Procedures-2011.pdf Upload files   Access-Procedures-2011.pdf Main aim of cohort, please briefly describe the main objectives of the cohort   This is a general population all-purpose cohort of adults, which includes some occupational data. Study design (please select as many as appropriate)   Prospective cohort Source population (please select as many as appropriate)   General population: National Comparators (please select as many as appropriate)   Internal study population Enrollment   Completed Age range at entry (main cohort)   Minimum Maximum Mean 40 69 55 Men at enrollment   250,000 Women at enrollment   250,000 Children (<18 years) at enrollment   0 Men at last follow-up   250,000 Women at last follow-up   250,000 Participation rate at enrollment (if known)   5 Comments   Access is open to all - apply through through the website - there is no need to contact the Principal Investigator 2. OUTCOME FOLLOW-UP Type of data for outcome follow-up (please select as many as appropriate)   Active (contact with participants) Death certificate Disease incidence records Hospital / physician diagnoses Active (contact with participants) (specify)   Only for special surveys Death certificate (specify)   Routine linkage Disease incidence records (specify)   Routine linkage, e.g. to cancer registries Hospital / Physician diagnoses (specify)   Linkage with hospital admissions First follow-up period (provide year)   2006 Last follow-up period (provide year)   ongoing Number of follow-ups after baseline (provide number)   500,000 Participation at last follow-up (if known)   100 Comments   Most follow-up is routine record linkage and is therefore close to 100% 3. OCCUPATIONAL EXPOSURES Source of exposure data collected (please select as many as appropriate)   Questionnaire, Personal (Self-reporting or interview) Questionnaire, Personal (Occupational/industry modules) Occupational history/time frame   Lifetime Occupational coding performed   No 4. OUTCOMES EVALUATED Baseline - type of outcome data collected (select more than one if applicable)   Biomarker (specify) Clinical/functional evaluation, e.g. spirometry, ECGs (specify) Death certificates Registry-based Specify: Clinical/functional evaluation, e.g. spirometry, ECGs   Many Specify: Biomarker   Many Registry-based   Cancer incidence Follow-up - type of outcome data collected (select more than one if applicable)   Death certificates Medical records Outcome type (please select as many as appropriate)   Mortality Morbidity Other health related outcomes   Biomarkers 5. BIOLOGICAL SAMPLES & ANALYSIS Biological samples collected   Blood Biological processing   DNA 6. Other Information Possibility for linkage to data registries/data enrichment via data linkage   Cancer incidence Hospital discharge Please describe plans that are funded or most likely to be funded   The cohort is gathering more information all of the time, particularly with record linkage