2020

1. IDENTIFICATION & BASIC DESCRIPTION Cohort name   Cohort of U.S. Pilots and Flight Engineers Country   United States Name   Raquel Velazquez-Kronen Institution   National Institute for Occupational Safety and Health Email   ohc0@cdc.gov Phone   513-533-8434 Upload files   Yong-et-al.-2014.pdf Contact Principal Investigator (name)   Please contact NIOSH by submitting the attached form Upload files   OMEGANET-cohort-interest-form_Final.pdf Participation in pooled analyses   The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses). Main aim of cohort, please briefly describe the main objectives of the cohort   Evaluate the association between occupational exposure to cosmic radiation and circadian rhythm disruption and cause-specific mortality Study design (please select as many as appropriate)   Retrospective cohort Source population (please select as many as appropriate)   Industry / occupation-based Comparators (please select as many as appropriate)   Internal study population External study population (includes SMR/SIR studies) Inclusion criteria   Employees who were employed as a pilot or/and flight engineer for at least one year before Pan Am closed in 1991, were U.S. citizens at the time of hire, and who worked at least one day at Pan Am after January 1, 1953 were included in the cohort. Enrollment   Completed Men at enrollment   5,958 Women at enrollment   6 Children (<18 years) at enrollment   0 2. OUTCOME FOLLOW-UP Type of data for outcome follow-up (please select as many as appropriate)   Death certificate Death certificate (specify)   Mortality is currently being updated though 2018 3. OCCUPATIONAL EXPOSURES Source of exposure data collected (please select as many as appropriate)   Job-employment records Methods for exposure assessment (please select as many as appropriate)   Data modelling Main categories   Physical agents Organisation of work including working time Physical agents   Radiation Physical agents | Radiation   Ionising Organisation of work including working time | Shift work   Night (permanent or rotating) 4. OUTCOMES EVALUATED Baseline - type of outcome data collected (select more than one if applicable)   Death certificates Follow-up - type of outcome data collected (select more than one if applicable)   Death certificates Outcome type (please select as many as appropriate)   Mortality 6. Other Information Possibility for linkage to data registries/data enrichment via data linkage   Mortality register