2020

1. IDENTIFICATION & BASIC DESCRIPTION Cohort name   Maternal Nutrition and Offspring's Epigenome (MANOE) Country   Belgium Name   Sara Pauwels Institution   KU Leuven Email   sara.pauwels@kuleuven.be Name of committee   UZ Leuven Ethical Committee Upload files   Thesis_final.pdf Is this cohort part of a consortium? (name consortium)   No Participation in pooled analyses   The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses). Main aim of cohort, please briefly describe the main objectives of the cohort   To assess the effect of maternal methyl-group donor intake during pregnancy on offspring DNA methylation of obesity related genes Study design (please select as many as appropriate)   Prospective cohort Source population (please select as many as appropriate)   Mother-child cohort Year(s) of enrollment   From To 2011 2019 Enrollment   Completed Men at enrollment   100 Women at enrollment   214 Children (<18 years) at enrollment   214 2. OUTCOME FOLLOW-UP Type of data for outcome follow-up (please select as many as appropriate)   Active (contact with participants) 3. OCCUPATIONAL EXPOSURES Occupational history/time frame   Current, at enrollment Occupational coding performed   Yes Occupation (specify coding system used)   ISCO 5. BIOLOGICAL SAMPLES & ANALYSIS Biological samples collected   Blood Biological processing   DNA Genetic and other lab analyses   Epigenomics 6. Other Information   Alcohol Anthropometry Demographics Diet Education Medical history Physical exercise Socioeconomic status Smoking