1. IDENTIFICATION & BASIC DESCRIPTION |
Cohort name
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INUENDO
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Country
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- Albania
- Greenland
- Poland
- Sweden
- Ukraine
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Name
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Gunnar Toft
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Institution
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Aarhus University Hospital
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Email
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guntof@rm.dk
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Upload files
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Contact Principal Investigator (name)
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Gunnar Toft
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Data access policy (briefly describe)
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Approval from all data collecting centers and data transfer agreeement is needed
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Participation in pooled analyses
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- The cohort is potentially interested in participating in pooled analyses of (European) occupational cohort studies (note pooled analyses also includes remote decentralized analyses that would not require any transfer of primary data as well as meta-analyses).
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Main aim of cohort, please briefly describe the main objectives of the cohort
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To study the effects of exposure to persistent organic pollutants on male and female fertility
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Study design (please select as many as appropriate)
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Source population (please select as many as appropriate)
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- General population: International
- Mother-child cohort
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Comparators (please select as many as appropriate)
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- Internal study population
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Inclusion criteria
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Pregnant women, >18 years of age, + husbands/spouses
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Enrollment
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Completed
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Age range at entry (main cohort)
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Minimum |
Maximum |
Mean |
18 |
64 |
30 |
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Men at enrollment
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797
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Women at enrollment
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2269
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Children (<18 years) at enrollment
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0
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Children (<18 years) at last follow-up
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1109
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Participation rate at enrollment (if known)
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43
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2. OUTCOME FOLLOW-UP |
Type of data for outcome follow-up (please select as many as appropriate)
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- Active (contact with participants)
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Active (contact with participants) (specify)
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- Follow up on childhood growth and development at 6-9 years of age
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3. OCCUPATIONAL EXPOSURES |
Source of exposure data collected (please select as many as appropriate)
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- Questionnaire, Personal (Self-reporting or interview)
- Questionnaire, Personal (Occupational/industry modules)
- Industry-based questionnaire
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Occupational history/time frame
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Current, at enrollment
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Occupational coding performed
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Yes
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Occupation (specify coding system used)
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Industry (specify coding system used)
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Methods for exposure assessment (please select as many as appropriate)
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Main categories
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- Pesticides
- Metals and metal oxides
- Other chemicals
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Pesticides | Insecticides
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Metals and metal oxides
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- Cadmium and all compounds
- Lead and all compounds
- Mercury, organic, inorganic
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Other chemicals | Flame retardants
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Other chemicals | Per- and polyfluoroalkyl substances (PFAS)
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- Per- and polyfluoroalkyl substances (PFAS)
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Other chemicals | Phthalates
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Other chemicals | PCBs
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- PCBs (polychlorinated biphenyls)
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4. OUTCOMES EVALUATED |
Baseline - type of outcome data collected (select more than one if applicable)
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- Questionnaire, individual (self-recording or interview)
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Follow-up - type of outcome data collected (select more than one if applicable)
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- Questionnaire, individual (self-recording or interview)
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Outcome type (please select as many as appropriate)
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Diagnostic groups based on ICD10
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- E Malnutrition and obesity
- F Mental disorders
- N Male and female related disorders
- O+P Pregnancy and labour
- Q After birth – child disorders
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E Malnutrition and obesity
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F Mental disorders
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- Personality and behavioural disorders
- Disorders of psychological development including autism and Aspergers syndrome
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N Male and female related disorders
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- Male infertility
- Abnormal menstrual cycle
- Female infertility
- Spontaneous abortion
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O+P Pregnancy and labour
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- Preterm delivery
- Other low birth weight
- Exceptionally large baby
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5. BIOLOGICAL SAMPLES & ANALYSIS |
Biological samples collected
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Specify: Other
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Buccal swabs
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Biological processing
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6. Other Information |
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- Alcohol
- Anthropometry
- Demographics
- Diet
- Education
- Environmental other (specify)
- Medical history
- Socioeconomic status
- Smoking
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Specify: Environmental other
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Biomarker measurements of environmental exposures as previously pecified
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