2020

1. IDENTIFICATION & BASIC DESCRIPTION Cohort name   Mexico City Prospective Study Country   Mexico Please provide any other information on the cohort location/s if needed   Mexico City Name   Roberto Tapia-Conyer Institution   National Autonomous University of Mexico Email   mcps-access@ndph.ox.ac.uk Name   Jonathan Emberson Institution   University of Oxford Email   mcps-access@ndph.ox.ac.uk Website   https://www.ctsu.ox.ac.uk/research/prospective-blood-based-study-of-150-000-individuals-in-mexico Name of committee   Mexican Ministry of Health; Mexican National Council for Science and Technology; University of Oxford Upload files   2006-Mexico-Cohort-Study-IJE.pdf Contact Principal Investigator (name)   Jonathan Emberson Data access policy (briefly describe)   We welcome requests from researchers who wish to access data from the Mexico City Prospective Study. If you are interested in obtaining data from the study for research purposes, or in collaborating with us on a specific research proposal, please visit our study website [https://www.ctsu. ox.ac.uk/research/prospective-blood-based-study-of-150- 000-individuals-in-mexico] where you can download our Data and Sample Access Policy in either English or Spanish. Is this cohort part of a consortium? (name consortium)   No Main aim of cohort, please briefly describe the main objectives of the cohort   To study the major social, lifestyle, physical, metabolic and genetic causes of disease in Mexican adults Study design (please select as many as appropriate)   Prospective cohort Source population (please select as many as appropriate)   General population: Regional Comparators (please select as many as appropriate)   Internal study population Inclusion criteria   Age 35 years or older from two districts of Mexico City Exclusion criteria   None Enrollment   Completed Age range at entry (main cohort)   Minimum Maximum Mean 35 No upper age limit Men at enrollment   ~50,000 Women at enrollment   ~100,000 Children (<18 years) at enrollment   0 2. OUTCOME FOLLOW-UP Type of data for outcome follow-up (please select as many as appropriate)   Death certificate First follow-up period (provide year)   1998 Last follow-up period (provide year)   2018 Number of follow-ups after baseline (provide number)   1 Participation at last follow-up (if known)   7 Comments   Between 2015-2019 a resurvey of 10,000 survivors was completed. 3. OCCUPATIONAL EXPOSURES Source of exposure data collected (please select as many as appropriate)   Questionnaire, Personal (Self-reporting or interview) Occupational history/time frame   Current, at enrollment Occupational coding performed   No Types of exposure measurements   Other (specify) Specify: Other   Questionnaire data, physical measurements and blood biomarkers Methods for exposure assessment (please select as many as appropriate)   Measurements (external sampling, biomarkers) Self-report Main categories   Other (specify) Main categories | Other | Specify: Other   None 4. OUTCOMES EVALUATED Baseline - type of outcome data collected (select more than one if applicable)   Biomarker (specify) Questionnaire, individual (self-recording or interview) Specify: Biomarker   A range of blood biomarkers Follow-up - type of outcome data collected (select more than one if applicable)   Death certificates Outcome type (please select as many as appropriate)   Mortality Diagnostic groups based on ICD10   Other (specify) Other (specify)   Death certificates are coded according to ICD-10 5. BIOLOGICAL SAMPLES & ANALYSIS Biological samples collected   Blood Biological processing   DNA Genetic and other lab analyses   Biomarkers (specify) Genomics / GWAS Genomics / Other genetics (specify) Metabolomics Specify: Biomarkers   A range of blood biomarkers have been measured. Specify: Other genetics   Exome sequence data 6. Other Information   Alcohol Anthropometry Demographics Diet Education Medical history Physical exercise Socioeconomic status Smoking